TITLE

Diagnostic Value of Polymerase Chain Reaction in Female Tuberculosis Leading to Infertility and Conception Rate After ATT

AUTHOR(S)
Puri, Suman; Bansal, Bhavana
PUB. DATE
January 2009
SOURCE
JK Science;Jan-Mar2009, Vol. 11 Issue 1, p31
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
To evaluate diagnostic value of PCR (Polymerase chain reaction) in female genital tuberculosis and to study conception rate after ATT (Anti tubercular treatment) in positive cases. Sixty infertile patients were investigated for presence of Mycobacterium tuberculosis (MTB) by PCR of endometrial curettings. PCR demonstrated MTB DNA in 28 patients. ATT was started in diagnosed cases which were followed up for two years for conception.All patients with laparoscopy suggestive of tuberculosis, more than 50% of those with a probable diagnosis and significant number of those with incidental findings were positive by PCR. Six PCR positive cases conceived within two years after taking ATT for 9 months. Four patients conceived spontaneously and two patients with intrauterine insemination. PCR offered increased sensitivity in determining tuberculosis etiology in female infertility and significant number of patients conceived after regular ATT.
ACCESSION #
43450288

 

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