A Decade of an Underestimated Nosocomal Pathogen- Acinetobacter In a Tertiary Care Hospital in Punjab

Oberoi, Aroma; Aggarwal, Aruna; Lal, Madan
January 2009
JK Science;Jan-Mar2009, Vol. 11 Issue 1, p24
Academic Journal
The present study was designed to know the prevalence of Acinetobacter in various clinical samples, their characterization, antibiotic susceptibility pattern and relevance in various clinical samples in Christian Medical College and Hospital, Ludhiana. Out of 3024 samples including pus, body fluids, blood, urine, drain tips, catheter tips and other appropriate samples, Acinetobacter was isolated in 255 (8.4%) samples. 66.6% isolates were sensitive to amikacin and 95% to cefaperazone/ sulbactam combination. This drug resistant nosocomial infection can be minimized to some extent by judicial use of antibiotics and adopting proper infection control measures.


Related Articles

  • Antimicrobial activity of the novel polymyxin derivative NAB739 tested against Gram-negative pathogens. Vaara, Martti; Sader, Helio S.; Rhomberg, Paul R.; Jones, Ronald N.; Vaara, Timo // Journal of Antimicrobial Chemotherapy (JAC);Mar2013, Vol. 68 Issue 3, p636 

    Objectives In spite of reported nephrotoxicity, polymyxins have been reinstated as the last-line therapy to treat infections caused by Gram-negative bacterial strains that are resistant to other agents. NAB739 has a cyclic portion identical to that of polymyxin B, but its linear peptide portion...

  • Quorum Sensing Inhibition: Targeting Chemical Communication in Gramnegative Bacteria. Persson, Tobias; Givskov, Michael; Nielsen, John // Current Medicinal Chemistry;2005, Vol. 12 Issue 26, p3103 

    Quorum sensing (QS) systems comprise a new therapeutic target potentially substitutive or complementary to traditional antibiotic treatment of chronic diseases. One route to disrupt the previously established interrelationship between pathogenesis and QS is by blocking the dual functioning...

  • Antimicrobials: A new drug for resistant bugs. Kåhrström, Christina Tobin // Nature Reviews Microbiology;Mar2015, Vol. 13 Issue 3, p126 

    The article discusses a study on the resistant mechanism of antibiotic teixobactin. It references the article "A new antibiotic kills pathogens without detectable resistance," by L. L. Ling and colleagues in the 2015 issue of the journal "Nature." Topics discussed include the unique chemical...

  • Multidrug-Resistant Acinetobacter spp.: Increasingly Problematic Nosocomial Pathogens. Kyungwon Lee; Dongeun Yong; Seok Hoon Jeong; Yunsop Chong // Yonsei Medical Journal;11/1/2011, Vol. 52 Issue 6, p879 

    Pathogenic bacteria have increasingly been resisting to antimicrobial therapy. Recently, resistance problem has been relatively much worsened in Gram-negative bacilli. Acinetobacter spp. are typical nosocomial pathogens causing infections and high mortality, almost exclusively in compromised...

  • Pharmacokinetics, Pharmacodynamics, and Tolerability Profile of Clinafloxacin. Stratton, C.W. // Clinical Drug Investigation;1998 Supplement 1, Vol. 15 Issue 1, p19 

    Summary Clinafloxacin is a broad-spectrum and highly potent member of the fluoroquinolone class of antibiotics, with enhanced activity against difficult-to-treat Gram-negative, Gram-positive, and anaerobic pathogens. It appears that the most important factor in terms of structure-activity is the...

  • Species of pathogens and drug selection in liver cirrhosis patients with sepsis. ZHANG Lan; CUI Enbo; BAO Chunmei // Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi;nov2013, Vol. 29 Issue 11, p858 

    Objective To identify the species of pathogens in liver cirrhosis patients with sepsis and screen out the effective antibiotics, and to provide a basis for effective clinical antimicrobial therapy. Methods Blood samples were collected from liver cirrhosis patients with suspected bloodstream...

  • Impact of Antibiotic Resistance in Gram-Negative Bacilli on Empirical and Definitive Antibiotic Therapy. Paterson, David L. // Clinical Infectious Diseases;9/15/2008 Supplement 1, Vol. 47, pS14 

    Serious infections with gram-negative pathogens continue to be associated with considerable mortality. Increasing antibiotic resistance in organisms such as Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae is contributing to difficulties with choosing antibiotics to...

  • In-Vitro Effects of Copper Nanoparticles on Common Bacterial Strains Implicated in Nosocomial Infections. Yousefi, Elham; Rafienia, Mohammad; Fazeli, Hossein; Kasai, Mohammad Zaman // Journal of Isfahan Medical School;Aug2013, Vol. 31 Issue 240, p830 

    Background: In recent years, the bacterial resistance to antibiotics has grown at a worrying speed. On the other hand, the rate of discovery of new antibiotics has failed to keep up with the emergence of resistance. Thus, there is a need for new approaches for fighting bacterial infections. We...

  • Microbial Colonization of Medical Devices and Novel Preventive Strategies. Shunmugaperumal, Tamilvanan // Recent Patents on Drug Delivery & Formulation;Jun2010, Vol. 4 Issue 2, p153 

    Upon implantation or insertion into patient's body for exerting theintended purpose like salvage of normal functions of vital organs, the medical devices are unfortunately becoming the sites of competition between host cell integration and microbial adhesion. Moreover, since there is an...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics