TITLE

The Role of Low Resistance Blood Flow Pathways in the Pathogenesis and Healing of Venous Leg Ulcers

AUTHOR(S)
Malanin, Ken; Kolari, Pertti J; Havu, Väinö K
PUB. DATE
May 1999
SOURCE
Acta Dermato-Venereologica;5/26/99, Vol. 79 Issue 2, p156
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
In an attempt to clarify the pathophysiology of haemodynamics in legs with venous ulcer we investigated the effect of a single intermittent pneumatic compression treatment on the peripheral resistance of leg arteries and the cutaneous laser Doppler flux in the leg. Eight patients with venous leg ulcers and 10 subjects with healthy legs were investigated. Doppler waveforms of the leg arteries and laser Doppler flux of the leg skin were recorded before and after a single intermittent pneumatic compression treatment with the subjects in a recumbent position. In the legs with venous ulcer, the peripheral resistance of the arteries was lower and the laser Doppler flux was greater, compared with healthy legs (p=0.003 and p=0.002, respectively). A single intermittent pneumatic compression treatment raised the peripheral resistance in the arteries of legs with ulcer and laser Doppler flux of the skin more in ulcer legs than in healthy legs (p=0.046 and p=0.034, respectively). These findings suggest that removal of oedema causes redistribution of skin blood flow in the legs with venous ulcer favouring the superficial capillary perfusion. This could explain why compression treatment promotes the healing of venous leg ulcers.
ACCESSION #
4342681

 

Related Articles

  • Cerebral Autoregulation Is Minimally Influenced by the Superior Cervical Ganglion in Two- Week-Old Lambs, and Absent in Preterm Lambs Immediately Following Delivery. Czynski, Adam J.; Terry, Michael H.; Deming, Douglas D.; Power, Gordon G.; Buchholz, John N.; Blood, Arlin B. // PLoS ONE;Dec2013, Vol. 8 Issue 12, p1 

    Cerebral vessels in the premature newborn brain are well supplied with adrenergic nerves, stemming from the superior cervical ganglia (SCG), but their role in regulation of blood flow remains uncertain. To test this function twelve premature or two-week-old lambs were instrumented with laser...

  • Abstracts of recent literature. J.E.E. // Journal of Rehabilitation Research & Development;Spring91, Vol. 28 Issue 2, p98 

    Presents an abstract of an article entitled `A Critical Review of Laser Doppler Flowmetry,' by A.N. Obeid, N.J. Barnett et al, reprinted from a 1990 issue of the `Journal of Medical Engineering and Technology.'

  • Abstracts of recent literature. Edelstein, Joan E.; Schein, Jerome D. // Journal of Rehabilitation Research & Development;Summer91, Vol. 28 Issue 3, p85 

    Presents an abstract of the article `Comparative Study of Two Laser Doppler Blood Flowmeters,' by N.J. Barnett, G. Dougherty and S.J. Pettinger published in the `Journal of Medical Engineering and Technology.'

  • Ankle-brachial index = zero. H.D.B. // Cortlandt Forum;04/25/97, Vol. 10 Issue 4, p106 

    Answers the question concerning the implications of a zero ankle-brachial index by Doppler in patient whose feet are cyanotic. Claim that this does not indicate that there will be runoff on an arteriogram.

  • Laser Doppler imaging of skin microcirculation. Svedman, Cecilia; Cherry, George W.; Strigini, Elizabeth; Ryan, Terence J. // Acta Dermato-Venereologica;5/1/1998, Vol. 78 Issue 2, p114 

    Laser Doppler imaging (LDI), a new technique which allows measurement of skin blood perfusion at a distance from the skin surface, was assessed methodologically in healthy volunteers. Each skin LDI value was based on virtually real-time measurements obtained from a number of discrete measuring...

  • Reproducibility of skin microcirculatory measurements in humans, with special emphasis on capillaroscopy. Abbink, E.J.; Wollersheim, H.; Netten, P.M.; Smits, P. // Vascular Medicine;2001, Vol. 6 Issue 4, p203 

    The reproducibility of capillaroscopic measurements of capillary blood cell velocity (CBV) in human nailfolds was investigated by use of the computerized system CapiFlow. Therefore, CBV measurements of two capillaries of each of three fingers together with laser Doppler fluxmetry (LDF) and skin...

  • Methods of Evaluation and Quantification of Microangiopathy in High Perfusion Microangiopathy (Chronic Venous Insufficiency and Diabetic Microangiopathy). Cesarone, M.R.; De Sanctis, M.T.; Incandela, L.; Belcaro, G.; Griffin, M.; Cacchio, M. // Angiology;Oct2001 Supplement, Vol. 52, pS3 

    Presents methods of evaluation and quantification of microangiopathy in high perfusion microangiopathy, chronic venous insufficiency and diabetic microangiopathy. Microcirculatory methods; Laser Doppler flowmetry; Strain-gauge plethysmography; Venous occlusion plethysmography.

  • Utility of a bedside doppler in tracking left ventricular... Chendrasekhar, Akella; Prabhakar, Ganga // American Surgeon;Aug1997, Vol. 63 Issue 8, p747 

    Presents a study to test the ability of a simple Doppler device to track diastolic dysfunction in hemorrhagic shock. Materials and methods used in the study; Presentation of the statistical data collected at each stage of the hemorrhagic shock model; Results of the study.

  • The FTc is not an accurate marker of left ventricular preload. Singer, Mervyn // Intensive Care Medicine;Jul2006, Vol. 32 Issue 7, p1089 

    A letter to the editor is presented to an article about the use of oesophageal Doppler to assess intravascular volume status and corrected flow time as a measure of left ventricular preload.

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics