TITLE

Stem cell treatment may offer Crohn's cure

PUB. DATE
July 2009
SOURCE
Gastrointestinal Nursing;Jul2009, Vol. 7 Issue 6, p4
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article discusses the Autologous Stem Cell Transplantation in Chrohn's Disease (Astic) trial. Researchers are comparing haematopoietic stem cell mobilization followed by high dose immuno-ablation and autologous stem cell transplantation with haematopoietic stem cell mobilization followed by best clinical practice.
ACCESSION #
43417056

 

Related Articles

  • Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. Flach, Johanna; Bakker, Sietske T.; Mohrin, Mary; Conroy, Pauline C.; Pietras, Eric M.; Reynaud, Damien; Alvarez, Silvia; Diolaiti, Morgan E.; Ugarte, Fernando; Forsberg, E. Camilla; Le Beau, Michelle M.; Stohr, Bradley A.; Méndez, Juan; Morrison, Ciaran G.; Passegué, Emmanuelle // Nature;8/14/2014, Vol. 512 Issue 7513, p198 

    Haematopoietic stem cells (HSCs) self-renew for life, thereby making them one of the few blood cells that truly age. Paradoxically, although HSCs numerically expand with age, their functional activity declines over time, resulting in degraded blood production and impaired engraftment following...

  • Bronchoscopy in haematopoietic stem cell transplant recipients may not be beneficial. Eccersley, Lydia R. J. // Thorax;Aug2007, Vol. 62 Issue 8, p683 

    The article presents a study which examines the significance of bronchoscopy to haemopoietic stem cell transplant (HSCT) recipients. It aimed to assess whether modifications in management-based on bronchoscopy results led to a survival advantage. The subject of the study were 1651 HSCT...

  • Effects of Allogeneic Hematopoietic Stem Cell Transplantation in Childhood and Adolescence. Vatanen, A. // Fertility Weekly;5/19/2014, p6 

    The article discusses a study on the allogeneic hematopoietic stem cell transplantation (HSCT) effects in childhood and adolescence. It also mentions the high risk of ovarian failure to adolescents who conditioned with total body irradiation (TBI) and busulfan (BU)-based regimes. It also...

  • Searching for alternative hematopoietic stem cell donors for pediatric patients. Rocha, V.; Locatelli, F. // Bone Marrow Transplantation;Jan2008, Vol. 41 Issue 2, p207 

    The use of alternative hematopoietic stem cell (HSC) donors has been witnessing important progress, mainly due to: (i) better HLA matching at the allelic level between donor and recipient in unrelated HSC transplantation (HSCT) translating into better patient outcome; (ii) better donor choice...

  • Regionally limited or rare infections: prevention after hematopoietic cell transplantation. Gea-Banacloche, J; Masur, H; da Cunha, C Arns; Chiller, T; Kirchhoff, L V; Shaw, P; Tomblyn, M; Cordonnier, C // Bone Marrow Transplantation;Apr2010, Vol. 45 Issue 4, p806 

    A correction to the article "Guidelines for preventing infectious complications among hematopoietic cell transplant recipients: a global perspective" that was published in 2009 issue is presented.

  • Cord Colitis Syndrome in Cord-Blood Stem-Cell Transplantation. Herrera, Alex F.; Soriano, Gabriela; Bellizzi, Andrew M.; Hornick, Jason L.; Ho, Vincent T.; Cutler, Corey S.; Antin, Joseph H.; Soiffer, Robert J.; Marty, Francisco M.; Baden, Lindsey R.; Ballen, Karen K. // New England Journal of Medicine;9/1/2011, Vol. 365 Issue 9, p815 

    Background: Diarrhea is a frequent complication of hematopoietic stem-cell transplantation (HSCT). Important causes of diarrhea after HSCT include acute graft-versus-host disease (GVHD), infections, and medications. After the transplantation and engraftment of hematopoietic stem cells from...

  • A New Method of Mobilization of Hematopoietic Stem Cells in Autologous Stem Cell Transplantation. Enikő, Kakucs; I., Benedek; Erzsébet, Benedek; Judit Beáta, Köpeczi; Aliz, Tunyogi; Monica, Istrati // Acta Medica Marisiensis;Aug2011, Vol. 57 Issue 4, p306 

    Background: Plerixafor is a selective and reversible antagonist of CXCR4 chemokine receptor indicated in combination with G-CSF (Granulocyte colony stimulating factor) to release haematopoietic stem cells (HSC) into the peripheral blood for collection and subsequent autologous transplantation...

  • Bacterial Genomics in Transplant-Related Colitis. BHATT, AMI S. // Oncologist;Oct2013 Supplement 1, Vol. 18, pS3 

    Significant and treatment-limiting morbidity and mortality are associated with the administration of cancer chemotherapy. Patients who have clear tumor responses to chemotherapy are not infrequently subjected to dose reductions or significant changes of otherwise efficacious regimens because of...

  • Hematopoietic Stem Cell Development, Niches, and Signaling Pathways. Chotinantakul, Kamonnaree; Leeanansaksiri, Wilairat // Bone Marrow Research;2012, p1 

    Hematopoietic stem cells (HSCs) play a key role in hematopoietic system that functions mainly in homeostasis and immune response. HSCs transplantation has been applied for the treatment of several diseases. However, HSCs persist in the small quantity within the body, mostly in the quiescent...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics