The Role of Nerve Signaling in Limb Genesis and Agenesis During Axolotl Limb Regeneration

Satoh, Akira; James, Michelle A.; Gardiner, David M.
July 2009
Journal of Bone & Joint Surgery, American Volume;Jul2009 Supplement 4, Vol. 91-A, p90
Academic Journal
The article describes the accessory limb model as a new assay for limb regeneration. It mentions that the model addresses the challenge of developing an appropriate assay that identified signals from nerves that function during the early stages of regeneration to induce the formation of the blastema. They authors indicate that in the model, a skin wound normally heals and regenerates the skin but does not form an ectopic limb.


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