Cell Signaling Regulation of Vertebrate Limb Growth and Patterning

Yingzi Yang; Kozin, Scott H.
July 2009
Journal of Bone & Joint Surgery, American Volume;Jul2009 Supplement 4, Vol. 91-A, p76
Academic Journal
The article describes the various links between different axes of limb development. It also provides examples of the ways in which genetic mutations or disrupted embryonic development can affect the signaling events and cause longitudinal deficiencies and malformations. It mentions that molecular and genetic studies indicated that disruptions of signaling events cause limb malformations, and cell signaling is important in regulating growth and patterning of vertebrate limbs.


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