Molecular Regulation of Limb Growth

Lyons, Karen; Ezaki, Marybeth
July 2009
Journal of Bone & Joint Surgery, American Volume;Jul2009 Supplement 4, Vol. 91-A, p47
Academic Journal
The article discusses the regulation and patterning of limb growth, as well as the osteocartilaginous elements in the limb. It mentions that the upper-limb bud appears in the human embryo at twenty-eight days after fertilization along the symmetrical lateral mesodermal plates which is known as the Wolff crest. The early limb bud is composed of a core of loose mesenchymal cells derived from the lateral plate mesoderm and an outer layer of epithelial cells from the ecdoderm.


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