Role of Platelet-Rich Plasma in Accelerating the Wound-Healing Process and Recovery in Patients Undergoing Operation for Pilonidal Sinus Disease: Preliminary Results

Efron, Jonathan
August 2009
World Journal of Surgery;Aug2009, Vol. 33 Issue 8, p1770
Academic Journal
The article offers the author's views on the role of platelet-rich plasma (PRP) in accelerating the wound-healing process and recovery in patients undergoing surgery for pilonidal sinus disease, studied by M. Spyridakis and colleagues. He notes that the cost of delivering the PRP is not discussed in Spyridakis's report. He states that though their pilot study is encouraging, more data from randomized trials is needed for assessing its safety rates.


Related Articles

  • The Role of the Platelet-Rich Plasma in Accelerating the Wound-Healing Process and Recovery in Patients Being Operated for Pilonidal Sinus Disease: Preliminary Results. Spyridakis, Michail; Christodoulidis, Gregory; Chatzitheofilou, Constantine; Symeonidis, Dimitris; Tepetes, Konstantinos // World Journal of Surgery;Aug2009, Vol. 33 Issue 8, p1764 

    Because of the poor quality of life that results from the open technique (open excision and packing) for surgically treating pilonidal cyst disease, several alternatives that accelerate the wound-healing process have been proposed. This study aimed to evaluate the effect of platelet-derived...

  • AN ANALYSIS OF A RAPID, SIMPLE, AND INEXPENSIVE TECHNIQUE USED TO OBTAIN PLATELET-RICH PLASMA FOR USE IN CLINICAL PRACTICE. Rutkowski, James L.; Thomas, Joseph M.; Bering, C. Larry; Speicher, Julie L.; Radio, Nicholas M.; Smith, Douglas M.; Johnson, David A. // Journal of Oral Implantology;2008, Vol. 34 Issue 1, p25 

    The use of platelet-rich plasma (PRP) has become more generally accepted, and implant dentists are using PRP more frequently to promote the healing of oral surgical and/or periodontal wounds. Critical elements of PRP are thought to be growth factors contained within the concentrated platelets....

  • Platelet concentrate vs. saline in a rat patellar tendon healing model. Spang, Jeffrey T.; Tischer, Thomas; Salzmann, Gian M.; Winkler, Tobias; Burgkart, Rainer; Wexel, Gabriele; Imhoff, Andreas B. // Knee Surgery, Sports Traumatology, Arthroscopy;Mar2011, Vol. 19 Issue 3, p495 

    Purpose: To evaluate single centrifuge platelet concentrate as additive for improved tendon healing. Platelet-rich plasma has been reported to improve tendon healing. Single centrifuge platelet concentration may increase platelet concentration enough to positively affect tendon healing. A single...

  • Experiencia clínica en el empleo de factores de crecimiento autólogos obtenidos de plasma rico en plaquetas. Echeverría, J. Montón; Pérez, Redondo S.; Bajo, G. J. Gómez // Cirugía Plástica Ibero-Latinoamericana;2007, Vol. 33 Issue 3, p155 

    This article intends to expose the state of the art related to the clinical use of autologous rich platelet plasma in different procedures which belong to the field of Plastic and Reconstructive Surgery. It is also referred our clinical experience related to this practice during a 30 month...

  • Platelet-Rich Plasma: A Promising Innovation in Dentistry. Tözüm, Tolga Fikret; Demiralp, Burak // Journal of the Canadian Dental Association;Nov2003, Vol. 69 Issue 10, p664 

    The article discusses a study which explores the evolution of platelet-rich plasma (PRP), a concentrated suspension of the growth factors found in platelets, and its specific effects on periodontal wound healing. It mentions the efforts of a variety of companies in developing systems for...

  • Use of platelet rich plasma to treat plantar fasciitis: design of a multi centre randomized controlled trial. Peerbooms, Joost C.; van Laar, Wilbert; Faber, Frank; Schuller, Hans M.; van der Hoeven, Henk; Gosens, Taco // BMC Musculoskeletal Disorders;2010, Vol. 11, p69 

    Background: If conservative treatment for chronic plantar fasciitis fails, often a corticosteroid injection is given. Corticosteroid injection gives temporarily pain reduction, but no healing. Blood platelets initiate the natural healing rate. GPS® gives an eightfold concentrate platelets of...

  • Developing recombinant HPA-1a-specific antibodies with abrogated Fcgamma receptor binding for the treatment of fetomaternal alloimmune thrombocytopenia. Ghevaert, Cedric; Wilcox, David A.; Fang, Juan; Armour, Kathryn L.; Clark, Mike R.; Ouwehand, Willem H.; Williamson, Lorna M. // Journal of Clinical Investigation;Aug2008, Vol. 118 Issue 8, p2929 

    Fetomaternal alloimmune thrombocytopenia (FMAIT) is caused by maternal generation of antibodies specific for paternal platelet antigens and can lead to fetal intracranial hemorrhage. A SNP in the gene encoding integrin beta3 causes a clinically important maternal-paternal antigenic difference;...

  • Silver-impregnated dressings reduce wound closure time in marsupialized pilonidal sinus. Koyuncu, Ayhan; Karada, Hakan; Kurt, Atilla; Aydin, Cengiz; Topcu, Omer // EWMA Journal;Oct2010, Vol. 10 Issue 3, p25 

    Objective: Sacrococcygeal pilonidal sinus disease is caused by in-grown-hairs between the buttocks. Surgery is the principal method of treatment. Several surgical methods should offer conditions of fast cicatrisation. In this study we evaluated the effects of silver-impregnated dressings* on...

  • Actualización bibliográfica sobre el uso de preparaciones ricas en plaquetas en la cicatrización de heridas. De Acosta Andino, D. A. Mateo; Porres Aguilar, M.; Makipour Jr., J.; Bedolla, E.; Vázquez Saldaña, D. G. // Cirugía Plástica Ibero-Latinoamericana;2010, Vol. 36 Issue 3, p231 

    Platelets store more than 20 growth factors in their granules. Their secretion promotes wound healing and repair. The intricate wound healing process involves not only the angiogenic platelet factors but also de anti-angiogenic ones. The process of platelet preservation, such as freezing,...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics