TITLE

Study of non-Hodgkin's lymphoma mortality associated with industrial pollution in Spain, using Poisson models

AUTHOR(S)
Ramis, Rebeca; Vidal, Enrique; García-Pérez, Javier; Lope, Virginia; Aragonés, Nuria; Pérez-Gómez, Beatriz; Pollán, Marina; López-Abente, Gonzalo
PUB. DATE
January 2009
SOURCE
BMC Public Health;2009, Vol. 9 Issue 1, p1
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: Non-Hodgkin's lymphomas (NHLs) have been linked to proximity to industrial areas, but evidence regarding the health risk posed by residence near pollutant industries is very limited. The European Pollutant Emission Register (EPER) is a public register that furnishes valuable information on industries that release pollutants to air and water, along with their geographical location. This study sought to explore the relationship between NHL mortality in small areas in Spain and environmental exposure to pollutant emissions from EPER-registered industries, using three Poisson-regression-based mathematical models. Methods: Observed cases were drawn from mortality registries in Spain for the period 1994-2003. Industries were grouped into the following sectors: energy; metal; mineral; organic chemicals; waste; paper; food; and use of solvents. Populations having an industry within a radius of 1, 1.5, or 2 kilometres from the municipal centroid were deemed to be exposed. Municipalities outside those radii were considered as reference populations. The relative risks (RRs) associated with proximity to pollutant industries were estimated using the following methods: Poisson Regression; mixed Poisson model with random provincial effect; and spatial autoregressive modelling (BYM model). Results: Only proximity of paper industries to population centres (>2 km) could be associated with a greater risk of NHL mortality (mixed model: RR:1.24, 95% CI:1.09-1.42; BYM model: RR:1.21, 95% CI:1.01-1.45; Poisson model: RR:1.16, 95% CI:1.06-1.27). Spatial models yielded higher estimates. Conclusion: The reported association between exposure to air pollution from the paper, pulp and board industry and NHL mortality is independent of the model used. Inclusion of spatial random effects terms in the risk estimate improves the study of associations between environmental exposures and mortality. The EPER could be of great utility when studying the effects of industrial pollution on the health of the population.
ACCESSION #
43226901

 

Related Articles

  • How to restrict liver biopsy to high-risk patients in early-stage Hodgkin's disease. Lieberz, D.; Sextro, M.; Paulus, U.; Franklin, J.; Tesch, H.; Diehl, V. // Annals of Hematology;Feb2000, Vol. 79 Issue 2, p73 

    Liver biopsy is an invasive diagnostic method for detecting liver involvement (LI) in Hodgkin's disease (HD). The aim of this retrospective study was to determine and evaluate a method for restricting liver biopsy to a subset of patients. Between 1988 and 1994, a total of 2016 patients with HD...

  • Health effects of acid aerosols on North American children: pulmonary function Dockery, Douglas W.; Raizenne, Mark; Damokosh, Andrew I.; Neas, Lucas M.; Ware, James H.; Speizer, Frank E.; Koutrakis, Petros; Spengler, John D. // Environmental Health Perspectives;May1996, Vol. 104 Issue 5, p506 

    No abstract available.

  • Small area study of mortality among people living near multiple sources of air pollution. Michelozzi, P.; Fusco, D.; Forastiere, F.; Ancona, C.; Dell'Orco, V.; Perrucci, C.A. // Occupational & Environmental Medicine;Sep1998, Vol. 55 Issue 9, p611 

    Reports on the analysis of mortality conducted to evaluate the potential health risk due to airborne contamination around multiple sources of air pollution in Rome, Italy. Computation of the standardized mortality ratios for men and women; Absence of association between proximity to industrial...

  • Non-Hodgkin's lymphomas of the large bowel-Clinical Characteristics, Prognostic Factors and Survival. Stanojević, G. Z.; Stojanović, M. P.; Stojanović, M. M.; Krivokapić, Z.; M. M. Jovanović; Katić, V. V.; Jeremić, M. M.; Branković, B. R. // Acta Chirurgica Iugoslavica;2008, Vol. 55 Issue 3, p109 

    The aims of this study were to review the clinical presentation of non-Hodgkin's lymphomas of the large bowel, to analyze the prognostic factors using univariate and multivariate methods, as well as the overall survival. We identified 24 cases at our clink between 1991 and 2005, based on...

  • Assessing risk and improving survival in lymphoma. Fields, Paul A.; Wrench, David J. // British Journal of General Practice;May2015, Vol. 65 Issue 634, p220 

    The authors reflect on two large case-control studies which determine symptom and sign risk profiles in the primary care setting patients with non-Hodgkin lymphoma (NHL). Topics discussed include assessment of clinical risk factors of the lymphoma, the importance of particular symptom and sign,...

  • Identifying populations at risk from environmental contamination from point sources. Williams, F.L.R.; Ogston, S.A. // Occupational & Environmental Medicine;Jan2002, Vol. 59 Issue 1, p2 

    Deals with a study which compared methods for defining the population at risk from a point source of air pollution. Methods; Results; Discussion.

  • Good idea, bad neighbour Bacon, David // Alternatives Journal;Winter1998, Vol. 24 Issue 1, p11 

    No abstract available.

  • SMOG'S YOUNGEST VICTIMS. Cheater, Mark // National Wildlife (World Edition);Apr/May2002, Vol. 40 Issue 3, p10 

    Examines the impact of air pollution on pregnant women in Los Angeles, California. Increase risk to giving birth to children with heart defects; Sources of carbon monoxide pollution; Views of Beate Ritz of the University of California on the findings.

  • Effects of Particulate Matter Exposure and Medication Use on Asthmatics. Silverman, F.; Hosein, H.R.; Corey, P.; Holton, S.; Tarlo, S.M. // Archives of Environmental Health;Jan/Feb92, Vol. 47 Issue 1 

    Investigates the effects of particulate matter, air pollution exposure and medication use on asthmatics in Toronto, Ontario. Association between pollution exposure and pulmonary function; Factors contributing to the pulmonary function of asthmatics; Details on the seasonal variation in...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics