TITLE

Surface-enhanced Raman scattering: realization of localized surface plasmon resonance using unique substrates and methods

AUTHOR(S)
Hossain, Mohammad Kamal; Kitahama, Yasutaka; Huang, Genin Gary; Xiaoxia Han; Ozaki, Yukihiro
PUB. DATE
August 2009
SOURCE
Analytical & Bioanalytical Chemistry;Aug2009, Vol. 394 Issue 7, p1747
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Surface-enhanced Raman scattering (SERS) enhancement and the reproducibility of the SERS signal strongly reflect the quality and nature of the SERS substrates because of diverse localized surface plasmon resonance (LSPR) excitations excited at interstitials or sharp edges. LSPR excitations are the most important ingredients for achieving huge enhancements in the SERS process. In this report, we introduce several gold and silver nanoparticle-based SERS-active substrates developed solely by us and use these substrates to investigate the influence of LSPR excitations on SERS. SERS-active gold substrates were fabricated by immobilizing colloidal gold nanoparticles on glass slides without using any surfactants or electrolytes, whereas most of the SERS-active substrates that use colloidal gold/silver nanoparticles are not free of surfactant. Isolated aggregates, chain-like elongated aggregates and two-dimensional (2D) nanostructures were found to consist mostly of monolayers rather than agglomerations. With reference to correlated LSPR and SERS, combined experiments were carried out on a single platform at the same spatial position. The isolated aggregates mostly show a broadened and shifted SPR peak, whereas a weak blue-shifted peak is observed near 430 nm in addition to broadened peaks centered at 635 and 720 nm in the red spectral region in the chain-like elongated aggregates. In the case of 2D nanostructures, several SPR peaks are observed in diverse frequency regions. The characteristics of LSPR and SERS for the same gold nanoaggregates lead to a good correlation between SPR and SERS images. The elongated gold nanostructures show a higher enhancement of the Raman signal than the the isolated and 2D samples. In the case of SERS-active silver substrates for protein detection, a new approach has been adopted, in contrast to the conventional fabrication method. Colloidal silver nanoparticles are immobilized on the protein functionalized glass slides, and further SERS measurements are carried out based on LSPR excitations. A new strategy for the detection of biomolecules, particularly glutathione, under aqueous conditions is proposed. Finally, supramolecular J-aggregates of ionic dyes incorporated with silver colloidal aggregates are characterized by SERS measurements and correlated to finite-difference time-domain analysis with reference to LSPR excitations. [Figure not available: see fulltext.]
ACCESSION #
43169026

 

Related Articles

  • Genetic fingerprinting helps sort out look-alikes.  // Agricultural Research;Dec93, Vol. 41 Issue 12, p8 

    Analyzes genetic fingerprinting as a technique that sorts out look-alikes by reading their DNA make-up. Genetic diversity; Human genome research; Germplasm; Comments.

  • Action at a distance. Eden, Sharon; Cedar, Howard // Nature;5/4/1995, Vol. 375 Issue 6526, p16 

    Informs about use of a genetic approach to identify the cis-acting elements involved in the genomic imprinting, as reported by Leighton et al in the May 1995 issue of Nature. Details of the work.

  • Nothing to rip your genes over. Jones, Chuck // LAN: Life Association News;Jul97, Vol. 92 Issue 7, p40 

    Announces the advice from American Academy of Actuaries that the public has nothing to fear from insurance companies if they ever begin using genetic testing in the underwriting process. Technological innovations in risk classification in insurance; Legislation focused on genetic testing.

  • Testing [eternity: traditional methods usually adequate. Dodd, Barbara E.; Lincoln, P.J. // British Medical Journal (Clinical Research Edition);12/5/1987, Vol. 295 Issue 6611, p1435 

    Examines the applicability of DNA fingerprinting in solving paternity problem inquiries in Great Britain. Relevance of blood group testing in the process; Background of paternity index employed in genetical investigations; Dimensions for interpretations.

  • DNA testing: Guilty or innocent? Westrup, Hugh // Current Science;11/4/94, Vol. 80 Issue 5, p14 

    Discusses various aspects of DNA fingerprinting. Uniqueness of DNA fingerprints; Difficulties in using DNA fingerprinting in crime detection; Accuracy; Laboratory error; Interpretation; Case of Stuart Heaton who was sentenced to life in prison for killing a teenager.

  • Principles and challenges of genome-wide DNA methylation analysis. Laird, Peter W. // Nature Reviews Genetics;Mar2010, Vol. 11 Issue 3, p191 

    Methylation of cytosine bases in DNA provides a layer of epigenetic control in many eukaryotes that has important implications for normal biology and disease. Therefore, profiling DNA methylation across the genome is vital to understanding the influence of epigenetics. There has been a...

  • Genes in black and white. Vines, Gail // New Scientist;7/8/95, Vol. 147 Issue 1985, p34 

    Focuses on the efforts of researchers on DNA fingerprinting to help forensic teams guess the criminal suspect's color and facial features. Analysis of the DNA tests; Plans on collection of data by the Human Genome Diversity Project; Practice of blood quantum criteria by the Bureau of Indian...

  • Scientists splice RNA with DNA.  // R&D Magazine;Mar95, Vol. 37 Issue 4, p11 

    Informs that DNA molecules are being used to cut RNA by Scripps Research Institute scientists as part of an antiviral drug development project. Hopes of scientists regarding the use of DNA molecules in drugs to fight viral infections.

  • GENOMIC SELECTION in IRELAND where we have come from, and where we are going. Berry, Donagh // Irish Farmers Monthly;Apr2011, p28 

    The article presents the author's views on genomic selection in Ireland that was first implemented in spring 2009. He provides a background of genomic selection which was introduced as a possible method to increase genetic gain by using information on an animal's DNA profile in 2001. He explores...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics