TITLE

Electrowetting on dielectric-based microfluidics for integrated lipid bilayer formation and measurement

AUTHOR(S)
Poulos, Jason L.; Nelson, Wyatt C.; Tae-Joon Jeon; Chang-Jin Kim; Schmidt, Jacob J.
PUB. DATE
July 2009
SOURCE
Applied Physics Letters;7/6/2009, Vol. 95 Issue 1, p013706
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We present a microfluidic platform for the formation and electrical measurement of lipid bilayer membranes. Using electrowetting on dielectric (EWOD), two or more aqueous droplets surrounded by a lipid-containing organic phase were manipulated into contact to form a lipid bilayer at their interface. Thin-film Ag/AgCl electrodes integrated into the device enabled electrical measurement of membrane formation and the incorporation of gramicidin channels of two bilayers in parallel.
ACCESSION #
43158437

 

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