TITLE

Statistical potentials extracted from protein structures: Are these meaningful potentials?

AUTHOR(S)
Ben-Naim, A.
PUB. DATE
September 1997
SOURCE
Journal of Chemical Physics;9/1/1997, Vol. 107 Issue 9, p3698
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Presents an inventory of factors that determine the stability of proteins. Pair potential of mean force obtained from distribution of residues in proteins of known structures; Validity of the interpretation of the quantities referred as statistical potentials.
ACCESSION #
4303208

 

Related Articles

  • The roles of stability and contact order in determining protein folding rates. Dinner, Aaron R.; Karplus, Martin // Nature Structural Biology;Jan2001, Vol. 8 Issue 1, p21 

    Reveals that both contact order and stability play important roles in determining the folding rate. Dependence of the calculated log k[subf] on c and δG.

  • Inflammation-Associated Nitrotyrosination Affects TCR Recognition through Reduced Stability and Alteration of the Molecular Surface of the MHC Complex. Madhurantakam, Chaithanya; Duru, Adil D.; Sandalova, Tatyana; Webb, John R.; Achour, Adnane // PLoS ONE;Mar2012, Vol. 7 Issue 3, p1 

    Nitrotyrosination of proteins, a hallmark of inflammation, may result in the production of MHC-restricted neoantigens that can be recognized by T cells and bypass the constraints of immunological self-tolerance. Here we biochemically and structurally assessed how nitrotyrosination of the...

  • Real-Time Dynamics of Emerging Actin Networks in Cell-Mimicking Compartments. Deshpande, Siddharth; Pfohl, Thomas // PLoS ONE;Mar2015, Vol. 10 Issue 3, p1 

    Understanding the cytoskeletal functionality and its relation to other cellular components and properties is a prominent question in biophysics. The dynamics of actin cytoskeleton and its polymorphic nature are indispensable for the proper functioning of living cells. Actin bundles are involved...

  • A new harvest of fluorescent proteins. Patterson, George H. // Nature Biotechnology;Dec2004, Vol. 22 Issue 12, p1524 

    The article presents information about new fluorescent proteins, including mCherry, mBanana, mOrange, mStrawberry, mTangerine and mHoneydew. The most prominent fluorescent proteins have been derived from the Aequorea victoria green fluorescent protein (avGFP)2,3, and these molecules have been...

  • Morphogenetic Gradients and the Stability of Boundaries Between Neighboring Morphogenetic Regions. Kasatkin, Victor; Prochiantz, Alain; Holcmana, David // Bulletin of Mathematical Biology;Jan2008, Vol. 70 Issue 1, p156 

    Generating morphogenetic gradients during early development is a fundamental step of positional signaling, which ultimately results in patterning and cell specialization. Based on morphogens propagation from cells to cells, we have presented a biophysical model in Holcman et al. (in press),...

  • Expression and Purification of SAK-fused Human Interferon Alpha in Escherichia coli. Salunkhe, Shardul; Prasad, Bhaskarjyoti; Sabnis-Prasad, Ketaki; Apte-Deshpande, Anjali; Padmanabhan, Sriram // Journal of Microbial & Biochemical Technology;2009, Vol. 1 Issue 1, p5 

    A method for improved refolding and purification of E. coli derived human Interferon -α (rhIFN α2b) from inclusion bodies as a Staphylokinase (SAK) fusion protein is described. Such a fusion protein did not require the supplementation of rare codons for expression and was found to be...

  • Preferential hydration and the exclusion of cosolvents from protein surfaces. Shimizu, Seishi; Smith, Derek J. // Journal of Chemical Physics;7/8/2004, Vol. 121 Issue 2, p1148 

    Protein stability is enhanced by the addition of osmolytes, such as sugars and polyols and inert crowders, such as polyethylene glycols. This stability enhancement has been quantified by the preferential hydration parameter which can be determined by experiments. To understand the mechanism of...

  • Enhancement of bacteriophage λ stability using a λ Q S mutant in the continuous culture of Escherichia coli. Oh, Jeong; Choi, Shin; Park, Tai // Bioprocess & Biosystems Engineering;Nov2010, Vol. 33 Issue 9, p1103 

    In this study, we used a bacteriophage λ Q S mutant that increased the stability of recombinant Escherichia coli during continuous culture. The operation was conducted in two stages: the first stage was carried out to promote cell growth, and the second stage was performed for product...

  • Non-covalent interactions: Fold globally, bond locally. Zondlo, Neal J. // Nature Chemical Biology;Aug2010, Vol. 6 Issue 8, p567 

    The article presents a study conducted by G. J. Bartlett and colleagues on the role of n→π* interactions in the stabilization of protein structure. The study shows that n→π* interactions are ubiquitous in proteins, which are likely to occur in α-helices and in...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics