Contemporary Clinical Opioid Use: Opportunities and Challenges

Lanier, William L.; Kharasch, Evan D.
July 2009
Mayo Clinic Proceedings;Jul2009, Vol. 84 Issue 7, p572
Academic Journal
The article discusses the challenges and opportunities related to contemporary opioid use. New techniques in drug delivery have augmented traditional routes of opioids administration to enhance patients' relief of pain. It is considered that the most worrisome opioid adverse effect has been respiratory depression. The challenges and opportunities associated with opioid use have led in the introduction of new drugs and techniques for established indications.


Related Articles

  • pethidine. Peters, Michael // BMA A-Z Family Medical Encyclopedia;2004, p603 

    An encyclopedia entry for "pethidine" is presented. It is a synthetic opioid analgesic drug that is used as a premedication and for the relief of pain following operations or during childbirth. The drug which can be addictive is similar to but less powerful than morphine. Nausea and vomiting are...

  • Long-Term Opioid Therapy Reconsidered. Von Korff, Michael; Kolodny, Andrew; Deyo, Richard A.; Chou, Roger // Annals of Internal Medicine;9/6/2011, Vol. 155 Issue 5, p325 

    In the past 20 years, primary care physicians have greatly increased prescribing of long-term opioid therapy. However, the rise in opioid prescribing has outpaced the evidence regarding this practice. Increased opioid availability has been accompanied by an epidemic of opioid abuse and overdose....

  • PROPOXYPHENE.  // Davis's Drug Guide for Nurses, 10th edition;2007, p998 

    The article presents information propoxyphene, an opioid analgesic to relieve pain. It is contraindicated in pregnant or lactating women. Some of its adverse reactions or side effects include dizziness, weakness, dysphoria, euphoria, headache, insomnia, paradoxical excitement and sedation. The...

  • La morina ¡no! que deprime el centro respiratorio y engancha. Sanmiguel, Mónica Lalanda; Olmo, Juan Antonio Alonso del // AMF: Actualización en Medicina de Familia;2011, Vol. 7 Issue 8, p467 

    No abstract available.

  • Improving oral health with dental colleagues. Marston, Anges // International Journal of Palliative Nursing;Jan2006, Vol. 12 Issue 1, p13 

    The article reports on the adverse effects of using opioid in palliative care patients. Indications showed that the drugs being used to relieve pain adversely affect the oral habit of these patients. It is in this regard that nurses' role in minimizing these adverse effects and improve oral...

  • Opioid Metabolism. Smith, Howard S. // Mayo Clinic Proceedings;Jul2009, Vol. 84 Issue 7, p613 

    Clinicians understand that individual patients differ in their response to specific opioid analgesics and that patients may require trials of several opioids before finding an agent that provides effective analgesia with acceptable tolerability. Reasons for this variability include factors that...

  • Time to reconsider role of systemic narcotics in chronic benign pain.  // Geriatrics;May1990, Vol. 45 Issue 5, p16 

    The article reports that the time has come to reconsider the role of systemic narcotics in the treatment of patients with chronic benign pain. Traditional objections to the use of opioids to treat nonmalignant pain include the fear of substantial risk of addiction, as well as clinical side...

  • Intrathecal analgesia: Time to consider it for your patient? Shaparin, Naum; Sim, Andrew; Pappagallo, Marco; Gritsenko, Karina; Carullo, Veronica; Tsukanov, Jessica; Kosharskyy, Boleslav // Journal of Family Practice;Mar2015, Vol. 64 Issue 3, p166 

    The article discusses the use of intrathecal (IT) drug delivery system as an effective alternative to systemic analgesics or antispasmodics. Topics discussed include the capability of IT analgesia to improve patients' quality of life, the complexity of using IT analgesia in patients with chronic...

  • Oxymorphone abuse.  // Reactions Weekly;Apr2015, Vol. 1546 Issue 1, p161 

    The article presents case report of a patient who developed diffuse retinal ischaemia and vision loss following intravenous abuse of oral oxymorphone.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics