Use of nonsteroidal antiinflammatory drugs was associated with increased risks for death and hospitalization for MI and HF

Siegel, David
June 2009
ACP Journal Club;6/23/2009, Vol. 150 Issue 6, p10
Academic Journal
The article discusses whether the use of nonsteroidal antiinflammatory drugs increases the risks of death and hospitalization in patients with myocardial infarction. A cohort study was conducted on 107 092 patients who were 30 years of age and had survived their first hospitalization for heart failure. It was observed that the use of nonsteroidal antiinflammatory drugs was associated with increased risks for death, hospitalization for myocardial infarction in patients with heart failure.


Related Articles

  • NSAID use among elderly increases risk of first-time hospitalization for heart failure.  // Formulary;Jul2006, Vol. 41 Issue 7, p313 

    The article reports a cohort study based in Great Britain which stated that the risk of first hospital admission because of heart failure (HF) was slightly higher at the initiation of non-steroidal anti-inflammatory drug (NSAID) treatment among patients with a pre-existing diagnosis of HF, and...

  • NSAID use linked to increased risk of hospitalization for heart failure.  // Clinical Advisor;Nov2016, Vol. 19 Issue 11, p14 

    No abstract available.

  • Rofecoxib use increases congestive heart failure risk compared to celecoxib and nonselective NSAIDs.  // Formulary;Jul2004, Vol. 39 Issue 7, p341 

    Reports on a study conducted by researchers at the Institute for Clinical Evaluative Sciences in Ontario to assess hospital admission rates for congestive heart failure in patients dispensed cyclooxygenase-2 inhibitors or nonselective nonsteroidal anti-inflammatory drugs (NSAID). Increased risk...

  • NSAIDs raise heart failure risk by 30%. Liddle, Rachel // GP: General Practitioner;5/26/2006, p1 

    This article cites a research study that has shown that use of nonsteroidal anti-inflammatory agents (NSAIDs) raise heart failure risk. The study has shown that even using NSAIDs for a short duration at a low dose increases the risk of admission to hospital with heart failure in people over 60...

  • Rofecoxib/ NSAIDs, not celecoxib: increased heart failure risk.  // Reactions Weekly;6/5/2004, Issue 1004, p3 

    Discusses research being done on the link between the use of rofecoxib, celecoxib and non-selective nonsteroidal anti-inflammatory drugs (NSAID) and the risk of hospitalization for congestive heart failure. Reference to a study by M. Mamdani et al, published in the May 29, 2004 issue of the...

  • Clinical digest. Long-term use of non-steroidal anti-inflammatories results predictable heart failure risk.  // Nursing Standard;9/25/2013, Vol. 28 Issue 4, p18 

    The article discusses the article "Vascular and Upper Gastrointestinal Effects of Non-Steroidal Anti-Inflammatory Drugs: Meta-Analyses of Individual Participant Drugs: Meta-Analyses of Individual Participant Data From Randomized Trials" published in "The Lancet" which found that the long term...

  • Review: NSAIDs increase GI and CV events; coxibs increase mortality. Baigent, C.; Lader, Ellis // Annals of Internal Medicine;10/15/2013, Vol. 159 Issue 8, pJC12 

    The article focuses on a meta-analysis that explored the risk for vascular and upper gastrointestinal (GI) events with nonsteroidal anti-inflammatory drugs (NSAIDs), and states that the study concluded that selective cyclooxygenase-2 (COX-2) inhibitors increase adverse outcomes compared with...

  • Acute coronary syndromes: Efficacy and safety of pioglitazone in patients with ST elevation myocardial infarction treated with primary stent implantation. Kaneda, H.; Shiono, T.; Miyashita, Y.; Takahashi, S.; Taketani, Y.; Domae, H.; Matsumi, J.; Mizuno, S.; Minami, Y.; Sugitatsu, K.; Saito, S. // Heart;Jul2009, Vol. 95 Issue 13, p22 

    Background: Recent studies have shown that thiazolidinediones reduce neointimal hyperplasia after bare metal stent (BMS) implantation, but this drug group sometimes cause fluid retention that may lead to heart failure. Objectives: To examine the safety and efficacy of pioglitazone in patients...

  • Avoid NSAIDs after Myocardial Infarction. Boyle, Andrew J. // Clinical Cardiology Alert;Jul2011, Vol. 30 Issue 7, p49 

    The article reports a Danish study by A. M. Schjerning-Olsen and colleagues which evaluated the effects of the use of nonsteroidal anti-inflammatory drugs (NSAIDs) and the duration of its use in adults after their first myocardial infarction (MI). The study concluded that even short-term...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics