Prevalence of linked angina and gastroesophageal reflux disease in general practice

Kato, Hirohito; Ishii, Takamasa; Akimoto, Tatsuo; Urita, Yoshihisa; Sugimoto, Motonobu; Shimatani, Tomohiko
April 2009
World Journal of Gastroenterology;4/14/2009, Vol. 15 Issue 14, p1764
Academic Journal
AIM: To evaluate the association between gastro-esophageal reflux diseases (GERD) and coronary heart diseases. METHODS: One thousand nine hundred and seventy consecutive patients who attended our hospital were enrolled. All of the patients who first attend our hospital were asked to respond to the F-scale questionnaire regardless of their chief complaints. All patients had a careful history taken, and resting echocardiography (ECG) was performed by physicians if the diagnostic necessity arose. Patients with ECG signs of coronary artery ischemia were defined as ST-segment depression based on the Minnesota code. RESULTS: Among 712 patients (36%) with GERD, ECG was performed in 171 (24%), and ischemic changes were detected in eight (5%). Four (50%) of these patients with abnormal findings upon ECG had no chest symptoms such as chest pain, chest oppression, or palpitations. These patients (0.6%; 4/712) were thought to have non-GERD heartburn, which may be related to ischemic heart disease. Of 281 patients who underwent ECG and did not have GERD symptoms, 20 (7%) had abnormal findings upon ECG. In patients with GERD symptoms and ECG signs of coronary artery ischemia, the prevalence of linked angina was considered to be 0.4% (8/1970 patients). CONCLUSION: The present study suggested that ischemic heart disease might be found although a patient was referred to the hospital with a complaint of GERD symptoms. Physicians have to be concerned about missing clinically important coronary artery disease while evaluating patients for GERD symptoms.


Related Articles

  • GASTRO-OESOPHAGEAL REFLUX RELATED PAIN IN ISCHAEMIC HEART DISEASE: A CONTROLLED CLINICAL TRIAL OF LANSOPRAZOLE. Talwar, V.; Wurm, P.; de Caestecker, J. S.; Gershlick, A. H. // Gut;Apr2004 Supplement 3, Vol. 53, pA62 

    The article presents a controlled clinical trial of lansoprazole to test the gastro-oesophageal reflux (GOR) related pain in ischaemic heart disease (IHD). GOR and IHD commonly coexist. IHD patients may mistake GOR induced pain for cardiac pain. lntra-oesophageal acid can trigger angina or...

  • GERD Can Mimic Symptoms of a Heart Attack.  // HealthFacts;Jun2001, Vol. 26 Issue 6, p2 

    Reports that symptoms of gastroesophageal reflux disease and esophageal spasm are often mistaken by doctors for angina, especially in women.

  • Trial Study on DENG Tie-tao's Coronary Heart Disease Capsules in Improving Patients' Quality of Life. Wu Huan-lin; Wang Xia; Li Xin-mei; Luo Wen-jie; Deng Tie-tao // Chinese Journal of Integrative Medicine;Sep2005, Vol. 11 Issue 3, p173 

    Objective: To assess the efficacy of the Coronary Heart Disease (CHD) Capsules worked out by Prof. Deng -- in improving quality of life of CHD patients of qi deficiency with phlegm and blood stasis syndrome. Method: According to the WHO's diagnosis criteria of CHD, a total of 93 stable angina...

  • A Clinical Study of Safflower Yellow Injection in Treating Coronary Heart Disease Angina Pectoris with Xin-Blood Stagnation Syndrome. Zhang Qiong; Peng Jian-hua; Zhang Xiang-nong // Chinese Journal of Integrative Medicine;Sep2005, Vol. 11 Issue 3, p222 

    Objective: To evaluate the clinical effect and safety of Safflower Yellow injection (SYI) in treating coronary heart disease angina pectoris (CHD-AP) with Xin-blood stagnation syndrome (XBSS). Methods: Adopted was the multi-centered, randomized, positive parallel controlled method, 448 patients...

  • Exertional gastro-oesophageal reflux: a mechanism for symptoms in patients with angina pectoris and normal coronary angiograms. Schofield, P.M.; Bennett, D.H.; Whorwell, P.J.; Brooks, N.H.; Bray, C.L.; Ward, C.; Jones, P.E. // British Medical Journal (Clinical Research Edition);6/6/1987, Vol. 294 Issue 6585, p1459 

    Examines the mechanism of exertional gastro-esophageal reflux in patients with angina pectoris and normal coronary angiograms. Factors causing chest pain; Methodology of treatment; Use of intravenous technique for inducing the occurrence of symptoms.

  • Chest pain and subsequent consultation for coronary heart disease: a prospective cohort study. Croft, Peter R.; Thomas, Elaine // British Journal of General Practice;Jan2007, Vol. 57 Issue 534, p40 

    Background Chest pain may not be reported to general practice but could be an important first sign of coronary heart disease (CHD). Aims To determine whether self reported chest pain predicts future consultation for CHD in those with no history of consultation for CHD. Design of study...

  • Variations in use of cardiology services in a health authority: Comparison of coronary artery... Payne, Nick; Saul, Carol // BMJ: British Medical Journal (International Edition);1/25/97, Vol. 314 Issue 7076, p257 

    Explores the relation between rates of coronary artery revascularization and prevalence of angina to assess whether use of health services reflects need. Determining prevalence of angina; Prevalence of symptoms and mortality from coronary heart disease compared with deprivation; Proxy measures...

  • Interaction between cigarettes and propranolol in treatment of angina pectoris. Fox, Kim; Jonathan, Anne; Williams, Huw; Selwyn, Andrew // British Medical Journal;7/19/1980, Vol. 281 Issue 6234, p191 

    Focuses on the interaction between cigarettes and propranolol in the treatment of angina pectoris. Effects of smoking in the heart; Effectivity of the treatment for angina pectoris; Signs of myocardial ischaemia.

  • In the Clinic: Stable Ischemic Heart Disease.  // Annals of Internal Medicine;1/7/2014, Vol. 160 Issue 1, p1TC1-1 

    The article presents answers to several questions related to Stable Ischemic Heart Disease (SIHD) related to its diagnosis and treatment including differentiating between patients with SIHD and unstable angina, diagnostic test for the disease and the goals of treatment.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics