Unusual presentations of eosinophilic gastroenteritis: Case series and review of literature

Sheikh, Rafiq A.; Prindiville, Thomas P.; Pecha, R. Erick; Ruebner, Boris H.; Maconi, Giovanni
May 2009
World Journal of Gastroenterology;5/7/2009, Vol. 15 Issue 17, p2156
Academic Journal
Eosinophilic gastroenteritis (EG) is an uncommon disease characterized by focal or diffuse eosinophilic infiltration of the gastrointestinal tract, and is usually associated with dyspepsia, diarrhea and peripheral eosinophilia. Diffuse gastrointestinal tract and colonic involvement are uncommon. The endoscopic appearance may vary from normal to mucosal nodularity and ulceration. Gastrointestinal obstruction is unusual and is associated with predominantly muscular disease. We present five unusual cases of EG associated with gastric outlet and duodenal obstruction. Two cases presented with acute pancreatitis and one had a history of pancreatitis. Four cases responded well to medical therapy and one had recurrent gastric outlet obstruction that required surgery. Four out of the five cases had endoscopic and histological evidence of esophagitis and two had colitis. Two patients had ascites. These cases reaffirm that EG is a disorder with protean manifestations and may involve the entire gastrointestinal tract. Gastric outlet and/or small bowel obstruction is an important though uncommon presentation of EG. It may also present as esophagitis, gastritis with polypoid lesions, ulcers or erosions, colitis and pancreatitis and may mimic malignancy.


Related Articles

  • Eosinophilic gastroenteritis mimicking pancreatic cancer. Christopher, V.; Thompson, M.H.; Hughes, S. // Postgraduate Medical Journal;Aug2002, Vol. 78 Issue 922, p498 

    Eosinophilic gastroenteritis is a condition characterised by eosinophilic infiltration of the gastrointestinal tract. Biliary obstruction is an unusual presentation. A case where the initial investigations were consistent with carcinoma of the head of pancreas but the resection specimen showed...

  • Enhanced therapeutic response with addition of Ioratadine in subserosal eosinophilic gastroenteritis. Salkić, Nermin N.; Mustedanagić-Mujanović, Jasminka; Jovanović, Predrag; Alibegović, Ervin // Medicinski Glasnik;Feb2013, Vol. 10 Issue 1, p178 

    A case of a 45-year-old Caucasian male initially reported with symptoms of acute intestinal obstruction was presented. Diagnostic tests revealed. presence of eosinophilic ascites with marked peripheral eosinophilia, a significant thickening of stomach and intestinal wall and infiltration of...

  • An Atypical Case of Eosinophilic Gastroenteritis Presenting as Hypovolemic Shock. Martillo, Miguel; Herman, Michael; Abed, Elie; Abed, Jean; Gurunathan, Rajan; Munot, Khushboo; Mankal, Pavan Kumar; Ionescu, Gabriel; Kotler, Donald P.; Shi, Wenjing // Case Reports in Gastroenterology;May-Aug2015, Vol. 9 Issue 2, p142 

    Eosinophilic gastroenteritis is an uncommon condition characterized by focal or diffuse infiltration of eosinophils in the gastrointestinal tract in the absence of secondary causes. The pathogenesis of this condition is not well understood and its clinical presentation depends on the segment and...

  • Bowel Obstruction. Waldman, Anne Robin; Held-Warmkessel, Jeanne // Clinical Journal of Oncology Nursing;Nov/Dec2001, Vol. 5 Issue 6, p281 

    Presents a case study on bowel obstruction. Laboratory examinations; Differential diagnosis; Discussion on the medical condition.

  • Eosinophilic Gastroenteritis with Eosinophilic Dermatitis. Jae Myung Cha; Joung Il Lee; Kwang Ro Joo; Hyun Phil Shin // Yonsei Medical Journal;1/1/2010, Vol. 51 Issue 1, p145 

    Eosinophilic gastroenteritis (EG) is characterized by eosinophilic infiltration of the bowel wall and variable gastrointestinal manifestations. Clinicians should have a high index of suspicion for EG when faced with gastrointestinal symptoms and peripheral eosinophilia to avoid incorrect...

  • Eosinophilic Gastroenteritis Mimicking Acute Appendicitis. Tran, De; Salloum, Leslie; Tshibaka, Cimenga; Moser, Robert // American Surgeon;Oct2000, Vol. 66 Issue 10, p990 

    Eosinophilic gastroenteritis is a rare entity that can be treated successfully with glucocorticoid therapy if the appropriate diagnosis is made. However, it may present with symptomatology mimicking acute surgical conditions. We present the case of a 26-year-old man who presented with diffuse...

  • Closed loop large bowel obstruction secondary to pancreatitis. Slavin, J.; Smedley, F. H.; Cahill, C. J. // Journal of the Royal Society of Medicine;Aug1990, Vol. 83 Issue 8, p530 

    The article presents a case study of pancreatitis in a 43-year old man with closed loop large bowel obstruction resulting in caecal necrosis. The man reported severe abdominal pain in the right iliac fossa. The pain was associated with constipation and abdominal distension. This was one of the...

  • Large Bowel Obstruction, a Delayed Complication of Severe Gallstone Pancreatitis. Lal, Neeraj; Whiting, John; Hejmadi, Rahul; Raman, Sudarsanam // Case Reports in Surgery;10/26/2016, p1 

    Colonic complications are rare after acute pancreatitis but are associated with a high mortality. Possible complications include mechanical obstruction, ischaemic necrosis, haemorrhage, and fistula. We report a case of large bowel obstruction in a 31-year-old postpartum female, secondary to...

  • Lithium.  // Reactions Weekly;7/10/2010, Issue 1309, p27 

    The article describes the case of a 35-year-old woman who developed adynamic ileus while under lithium treatment regimen for bipolar disorder.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics