Incidence of bacterial meningitis (2001-2005) in Lazio, Italy: the results of a integrated surveillance system

Rossi, Paolo Giorgi; Mantovani, Jessica; Ferroni, Eliana; Forcina, Antonio; Stanghellini, Elena; Curtale, Filippo; Borgia, Piero
January 2009
BMC Infectious Diseases;2009, Vol. 9 Issue 1, Special section p1
Academic Journal
Background: Monitoring the incidence of bacterial meningitis is important to plan and evaluate preventive polices. The study's aim was to estimate the incidence of bacterial meningitis by aetiological agent in the period 2001-2005, in Lazio Italy (5.3 mln inhabitants). Methods: Data collected from four sources -- hospital surveillance of bacterial meningitis, laboratory information system, the mandatory infectious diseases notifications, and hospital information system -- were combined into a single archive. Results: 944 cases were reported, 89% were classified as community acquired. S. pneumoniae was the most frequent aetiological agent in Lazio, followed by N. meningitis. Incidence of H. influenzae decreased during the period. 17% of the cases had an unknown aetiology and 13% unspecified bacteria. The overall incidence was 3.7/100,000. Children under 1 year were most affected (50.3/ 100.000), followed by 1-4 year olds (12.5/100,000). The percentage of meningitis due to aetiological agents included in the vaccine targets, not considering age, is 31%. Streptococcus spp. was the primary cause of meningitis in the first three months of life. The capture-recapture model estimated underreporting at 17.2% of the overall incidence. Conclusion: Vaccine policies should be planned and monitored based on these results. The integrated surveillance system allowed us to observe a drop in H. influenzae b meningitis incidence consequent to the implementation of a mass vaccination of newborns.


Related Articles

  • Three Cases of Invasive Meningococcal Disease Caused by a Capsule Null Locus Strain Circulating among Healthy Carriers in Burkina Faso. Findlow, Helen; Vogel, Ulrich; Mueller, Judith E.; Curry, Alan; Njanpop-Lafourcade, Berthe-Marie; Claus, Heike; Gray, Stephen J.; Yaro, Seydou; Traoré, Yves; Sangaré, Lassana; Nicolas, Pierre; Gessner, Bradford D.; Borrow, Ray // Journal of Infectious Diseases;4/1/2007, Vol. 195 Issue 7, p1071 

    During reinforced surveillance of acute bacterial meningitis in Burkina Faso, meningococcal strains of phenotype NG:NT:NST were isolated from cerebrospinal fluid samples from 3 patients. The strains were negative for the ctrA gene but were positive for the crgA gene. Molecular typing revealed...

  • Costs for Households and Community Perception of Meningitis Epidemics in Burkina Faso. Colombini, Anaïs; Bationo, Fernand; Zongo, Sylvie; Ouattara, Fatoumata; Badolo, Ousmane; Jaillard, Philippe; Seini, Emmanuel; Gessner, Bradford D.; da Silva, Alfred // Clinical Infectious Diseases;11/15/2009, Vol. 49 Issue 10, p1520 

    Bacterial meningitis in the African meningitis belt remains 1 of the most serious threats to health. The perceptions regarding meningitis in local populations and the cost of illness for households are not well described. We conducted an anthropologic and economic study in Burkina Faso, in the...

  • Meningitis in Chad, Niger and Nigeria: 2009 epidemic season.  // Weekly Epidemiological Record;2/19/2010, Vol. 85 Issue 8, p57 

    The article focuses on meningitis epidemic patterns and response activities in Chad, Niger and Nigeria between January and May, 2009. It aims at examining achievements made and problems encountered in the three countries in order to identify opportunities for improvement. The epidemic in Nigeria...

  • Past outbreaks of meningococcal meningitis in the WHO South-East Asia Region - a brief overview.  // Weekly Epidemiological Record;5/20/2005, Vol. 80 Issue 20, p179 

    This article focuses on overview of meningococcal meningitis in the WHO South-East Asia Region. Meningococcal disease is endemic in Delhi and sporadic cases of meningococcal meningitis have occurred in Delhi in previous years. In addition, outbreaks of meningococcal meningitis in and around...

  • Meningitis due to Escherichia Coli 0126:B16. Zoumboulakis, Dimitri; Karaboula, Katherine; Albanis, Vlassis; Kiossoglou, Kosmas A. // Clinical Pediatrics;Oct1972, Vol. 11 Issue 10, p603 

    Focuses on meningitis due to Escherichia coli 0126:B16. Discussion of a fatal case in a 14-year-old girl.

  • Enhanced surveillance of epidemic meningococcal meningitis in Africa: a three-year experience.  // Weekly Epidemiological Record;9/16/2005, Vol. 80 Issue 37, p313 

    The article discusses epidemic meningococcal meningitis in Africa. Meningococcal meningitis is a bacterial infection of the meninges, the thin lining that surrounds the brain and spinal cord, whose common symptoms are sudden onset of headache, high fever, stiff neck and sensitivity to light. The...

  • Meningococcal disease in the African meningitis belt.  // Weekly Epidemiological Record;3/7/2008, Vol. 83 Issue 10, p90 

    The article focuses on the meningococcal disease activity in the African meningitis belt, the area at sub-Saharan Africa that stretches from Senegal in the west to Ethiopia in the east. The levels of meningitis activity were 29 percent lower than what was reported in 2007. According to the...

  • Surgical Aspects of Nontuberculous Bacterial Meningitis in Infancy and Childhood. Adeloye, Adelola; Oyedeji, G. A. // Clinical Pediatrics;Oct1973, Vol. 12 Issue 10, p589 

    At the University College Hospital, Ibadan, Nigeria, congenital malformations of the central nervous system were important predisposing factors to meningitis. Among 80 patients who survived the acute illnes, the main complications encountered, in order of frequency, were hydrocephalus (12),...

  • Fatal tuberculous meningitis caused by immune restoration disease. Huttner, Hagen; Kollmar, Rainer; Hug, Andreas; Meisel, Fabian; Kress, Bodo; Schwab, Stefan // Journal of Neurology;Dec2004, Vol. 251 Issue 12, p1522 

    Discusses a case of fatal tuberculous meningitis caused by immune restorate disease. Pathophysiology; Treatment options.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics