Diffuse large B-cell lymphoma of the uterine cervix: A rare case managed novellv

Baijal, Gunjan; Vadiraja, B. M.; Fernandes, Donald J.; Vidyasagar, M. S.
April 2009
Journal of Cancer Research & Therapeutics;Apr-Jun2009, Vol. 5 Issue 2, p140
Academic Journal
Non-Hodgkin's lymphoma (NHL) of the uterine cervix is exceedingly rare. The management of the disease is not standardized. A 44-year-old lady presented with a history of bleeding pervaginum and a foul-smelling discharge of 2 months' duration. A 7 × 7 growth was seen in the cervix. A biopsy revealed it to be a CD20-positive diffuse large B-cell (DLBCL)-type NHL. She was diagnosed as stage IE after staging work-up, and managed with three courses of rituximab, cyclophosphamide, vincristine, adriamycin, and prednisolone followed by external beam radiotherapy (46 Gy in 23 fractions) by 3D conformal technique. She attained a complete response, and has been in remission for 1 year 3 months.


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