TITLE

APLICABLIDADE DA SIALOMETRIA E INSTRUMENTOS DE AVALIAÇÀO DE QUEIXAS SECAS NUMA CONSULTA DE SÍNOROMA DE SJÖGREN

AUTHOR(S)
Barcelos, Filipe; Vaz Patto, José; Parente, Manuela; Medeiros, Dina; Sousa, Miguel; Figueiredo, Rui; Miguel, Cláudia; Teixeira, Ana
PUB. DATE
April 2009
SOURCE
Acta Reumatológica Portuguesa;2009, Vol. 34 Issue 2, p212
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Objectives: To evaluate the applicability and utility of unstimulated syalometry and instruments of evaluation of sicca complaints in a Sjögren's syndrome outpatient clinic. Material and Methods: We performed unstimulated syalometry to 45 consecutive Primary Sjögren's Syndrome patients (PSS) and 21 healthy asymptomatic individuals age and sex-matched. PSS patients were further evaluated with Schirmer's test. We applied 3 published questionnaires to PSS patients: «Xerostomia Inventory» (XI), «Oral Health Impact Profile-short form» (OHIP) and «Ocular Surface Disease Index» (OSDI), and correlated the results with syalometry and Schirmer's test. Statistical analysis was performed with SPSS (Mann-Whitney U-test and Spearman's correlation). Results: Salivary flux was significantly lower in PSS patients, as compared to controls (0.08±0.01 ml/min versus 0.38±0.25 mI/min, p=0.000), and decreased with age. Syalometry didn't correlate with Schirmer's test. OHIP scores (mean 26.8 points, ranging from 2 to 43 for a maximum of 56 points) didn't correlate with syalometry neither with Schirmer's test, but showed an association with the XI (p<0.0005) and USDI (p<0.0005) tests. The Xl questionnaire (mean 28.4 points, ranging from 11 to 41 for a maximum of 44 points) correlated with syalometry (p=0.018), with the OHIP questionary (p<0.0005) and with the USDI scale (p=0.004), although it didn't correlate with Schirmer's test. USD1 scores (mean 56.5 points, ranging from 7 to 90 for a maximum of 100 points) didn't correlate with Schirmer's test neither with syalometry, but associated with the XI (p=0.004) and OHIP (p<0.0005) scales. Conclusions: Unstimulated syalometry is useful in the evaluation of patients suspected of suffering from Sjögren's syndrome, since it can confirm salivary hypofunction in a quick and cheap manner, allowing to differentiate between healthy individuals and patients. In a specialized clinic, the immediate availability of a salivary functional test is important in the classification of PSS or sicca syndrome. The xerostomia and xerophtalmia impact scales were mutually concordant, and since they evaluate the effects of the disease through time, could be helpful in our daily consultation.
ACCESSION #
42430648

 

Related Articles

  • Oral Balance: Benefits in Patients with Xerostomia.  // Biological Therapies in Dentistry;Apr/May2005, Vol. 20 Issue 6, p21 

    Provides information on a study that examined the benefits of Oral Balance gel in xerostomic patients with primary Sjögren's syndrome. Health risk of the patients; Methodology of the study; Findings of the study.

  • Sjõgren Syndrome. Vohr, Hans-Werner // Encyclopedic Reference of Immunotoxicology;2005, p590 

    A definition of the term "Sjögren syndrome" is presented. It refers to a chronic systematic inflammatory disorder characterized by dryness of mucus membranes. The term is also related to systemic autoimmunity.

  • Endothelıal dysfunctıon ın patıents wıth prımary Sjögren’s syndrome. Pirildar, Timur; Tikiz, Canan; Özkaya, Sabriye; Tarhan, Serdar; Ütük, Ozan; Tikiz, Hakan; Tezcan, Uğur Kemal // Rheumatology International;Sep2005, Vol. 25 Issue 7, p536 

    The aim of this study was to determine the endothelial function in patients with primary Sjögren’s syndrome (SS). We also aimed to determine whether endothelial (dys)function correlates with extraglandular manifestations, specific autoantibodies and the severity of salivary gland...

  • Lymphoma of the parotid gland in Sj�gren's syndrome. Palacios, Enrique; Larusso, Giovanni; Rojas, Rafael; Ram�rez, Guadalupe // ENT: Ear, Nose & Throat Journal;Mar2004, Vol. 83 Issue 3, p156 

    Deals with the development of mucosa-associated lymphoid tissue (MALT) lymphomas in patients with Sj�gren's syndrome. Information on Sj�gren's syndrome; Percentage of patients in the U.S. with Sj�gren's syndrome who develop MALT lymphomas; Result of the examination of a...

  • Diagnosis and Management of Salivary Dysfunction. Valdez, Ingrid H.; Fox, Philip C. // Critical Reviews in Oral Biology & Medicine;1993, Vol. 4 Issue 3, p271 

    Salivary gland dysfunction may occur as a result of common medications, cancer therapy, or Sjögren's syndrome. Affected patients may develop significant oral, dental, and upper gastrointestinal sequelae. This article reviews the basic elements in diagnosis of salivary dysfunction, including...

  • Is Sjögren's Linked To Lymphoma? Karpecki, Paul M. // Review of Optometry;11/15/2004, Vol. 141 Issue 11, p127 

    Recognizes the association of Sjögren's syndrome with certain type of cancers. Effect of Sjögren's syndrome on multiple systems; Details on the incidence of lymphoma among women with keratoconjunctivitis sicca; History of swollen salivary glands.

  • Conjunctival epithelium improvement after systemic pilocarpine in patients with Sjögren's syndrome. Aragona, P.; Di Pietro, R.; Spinella, R.; Mobrici, M. // British Journal of Ophthalmology;Feb2006, Vol. 90 Issue 2, p166 

    Aim: To evaluate the effect of oral pilocarpine treatment on conjunctival epithelium of patients with Sjögren's syndrome (SS). Methods: 15 primary SS patients were included in this prospective, single masked, comparative study. Patients underwent oral pilocarpine treatment for 2 months and...

  • The Gastrointestinal Manifestations of Sjögren's Syndrome. Slieikh, Shahzad H.; Shaw-Stiffel, Thomas A. // American Journal of Gastroenterology;Jan1995, Vol. 90 Issue 1, p9 

    Sjögren's syndrome (SS) is an autoimmune exocrinopathy that primarily affects the salivary glands but can also involve almost any other part of the gut. The most distressing manifestation of SS is xerostomia secondary to destruction of the salivary glands. The lack of saliva also leads to...

  • Nephrocalcinosis: a rare presenting manifestation of primary Sjögren's syndrome. Rajput, Rajesh; Sehgal, Ashish; Jain, Deepak; Sen, Rajeev; Saini, Ompal // Modern Rheumatology (Springer Science & Business Media B.V.);Jun2012, Vol. 22 Issue 3, p479 

    Renal involvement in primary Sjögren's syndrome (pSS) is not uncommon. Autoimmune tubulointerstitial disorders and distal renal tubular acidosis (dRTA) account for majority of the cases of renal involvement. While dRTA may precede the onset of sicca syndrome in pSS, nephrocalcinosis as a...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics