Body Mass Index and Risk, Age of Onset, and Survival in Patients With Pancreatic Cancer

Morris, Jeffrey S.; Hassan, Manal M.; Day, S. Sue; Bondy, Melissa I.; Abbruzzese, James L.; Donghui Li; Jun Liu
June 2009
JAMA: Journal of the American Medical Association;6/24/2009, Vol. 301 Issue 24, p2553
Academic Journal
The article focuses on a study which determined the association between body mass index (BMI) over a lifetime and pancreatic cancer risk, age at onset and overall patient survival. Height and body weight histories were collected through personal interviews in 841 patients with pancreatic adenocarcinoma and 754 healthy individuals. The associations were examined using unconditional logistic regression, linear regression and Cox proportional hazard regression models. An increased risk was found on individuals who were overweight or obese from the ages 14 to 39 years. A strong association was also found in men by mean BMI from the ages 14 to 59 years than in women and in smokers than nonsmokers.


Related Articles

  • Relationship between body mass index and percent body fat in aging females. Ewing, B. A.; Godard, M. P. // International Journal of Body Composition Research;2010, Vol. 8 Issue 4, p131 

    Background: The purpose of this study was to compare the relationship between body fat percent utilizing Bod Pod (BF%) and body mass index (BMI) in premenopausal, perimenopausal, and postmenopausal women between the ages of 18-71 years. Methods: BF%, BMI, bioelectrical impedance, waist-to-hip,...

  • Validity of predictive equations for resting energy expenditure among Iranian women. Shaneshin, Mahboubeh; Rezazadeh, Arezoo; Jessri, Mahsa; Neyestani, Tirang; Rashidkhani, Bahram // Asia Pacific Journal of Clinical Nutrition;Dec2011, Vol. 20 Issue 4, p646 

    Objectives: To determine the resting metabolic rate (RMR) in a sample of Iranian women, and to evaluate the validity of predictive equations for estimating RMR in normal and obese subjects. Methods: This cross-sectional study was conducted on a total of 187 healthy women aged 18-45 years....

  • Adiposity and cancer risk: new mechanistic insights from epidemiology. Renehan, Andrew G.; Zwahlen, Marcel; Egger, Matthias // Nature Reviews Cancer;Aug2015, Vol. 15 Issue 8, p484 

    Excess body adiposity, commonly expressed as body mass index (BMI), is a risk factor for many common adult cancers. Over the past decade, epidemiological data have shown that adiposity-cancer risk associations are specific for gender, site, geographical population, histological subtype and...

  • Body mass index and physical activity as risk factors for pancreatic cancer: the Multiethnic Cohort Study. Ute Nöthlings; Lynne Wilkens; Suzanne Murphy; Jean Hankin; Brian Henderson; Laurence Kolonel // Cancer Causes & Control;Mar2007, Vol. 18 Issue 2, p165 

    AbstractObjective??To examine body mass index (BMI) and physical activity as risk factors for pancreatic cancer.Methods??Eight-year prospective data from 77,255 men and 90,175 women including 237 and 235 pancreatic cancer cases, respectively, in the Hawaii-Los Angeles Multiethnic Cohort Study...

  • Body Mass Index and Cancer Risk: The Evidence for Causal Association. Renehan, Andrew G.; Egger, Matthias; Zwahlen, Marcel // Open Obesity Journal;2010 Special Issue, p12 

    Increased body mass index (BMI), as an approximation of body adiposity, is a risk factor for developing several adult malignancies. To quantify these risks, we reported a comprehensive systematic review (Lancet 2008; 371: 569-78) of prospective observational studies determining associations...

  • Regional trends in obesity and overweight among Austrian adults between 1973 and 2007. Großschädl, Franziska; Stronegger, Willibald Julius // Wiener Klinische Wochenschrift;Jun2012, Vol. 124 Issue 11/12, p363 

    This paper examines regional changes in the prevalence of overweight (BMI ³ 25 kg/m²) and obesity (BMI ³ 30 kg/m²) among Austrian adults (aged ³ 20 years) during a 35-year period, taking into account the social inequality with regard to obesity. Self-reported data from five...

  • Association between variations in the fat mass and obesity-associated gene and pancreatic cancer risk: a case-control study in Japan. Yingsong Lin; Junko Ueda; Kiyoko Yagyu; Hiroshi Ishii; Makoto Ueno; Naoto Egawa; Haruhisa Nakao; Mitsuru Mori; Keitaro Matsuo; Shogo Kikuchi; Lin, Yingsong; Ueda, Junko; Yagyu, Kiyoko; Ishii, Hiroshi; Ueno, Makoto; Egawa, Naoto; Nakao, Haruhisa; Mori, Mitsuru; Matsuo, Keitaro; Kikuchi, Shogo // BMC Cancer;2013, Vol. 13 Issue 1, p1 

    Background: It is clear that genetic variations in the fat mass and obesity-associated (FTO) gene affect body mass index and the risk of obesity. Given the mounting evidence showing a positive association between obesity and pancreatic cancer, this study aimed to investigate the...

  • Central adiposity, obesity during early adulthood, and pancreatic cancer mortality in a pooled analysis of cohort studies. Genkinger, J. M.; Kitahara, C. M.; Bernstein, L.; de Gonzalez, A. Berrington; Brotzman, M.; Elena, J. W.; Giles, G. G.; Hartge, P.; Singh, P. N.; Stolzenberg-Solomon, R. Z.; Weiderpass, E.; Adami, H.-O.; Anderson, K. E.; Beane-Freeman, L. E.; Buring, J. E.; Fraser, G. E.; Fuchs, C. S.; Gapstur, S. M.; Gaziano, J. M.; Helzlsouer, K. J. // Annals of Oncology;Nov2015, Vol. 26 Issue 11, p2257 

    Background: Body mass index (BMI), a measure of obesity typically assessed in middle age or later, is known to be positively associated with pancreatic cancer. However, little evidence exists regarding the influence of central adiposity, a high BMI during early adulthood, and weight gain after...

  • The Relationship between Daily Steps and Body Composition in Postmenopausal Women. Krumm, Emily M.; Dessieux, Olivera L.; Andrews, Pamela; Thompson, Dixie L. // Journal of Women's Health (15409996);Mar2006, Vol. 15 Issue 2, p202 

    Purpose: The purpose of this study was to examine the relationship between pedometer-determined physical activity (PA) measured in steps per day and adiposity in postmenopausal women. Methods: Ninety-three women aged 60.9 ± 5.8 years participated in the study. Relative body fatness was...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics