PPIs and clopidogrel--Bad combination

Elliott, William T.
July 2009
Travel Medicine Advisor;Jul2009 Pharmacology Watch, p1
The article discusses a May 2009 study presented to the Society for Cardiovascular Angiography and Interventions (SCAI) which urges the discontinuance of a routine combination of clopidogrel (PLAVIN) and proton pump inhibitors (PPI) to patients who underwent coronary stenting. Recovery rate was seen as higher on evaluated patients who took clopidogrel alone than combined with PPI. SCAI believes more research is recommended even as it points out from other studies of similar findings. It further advises that H2 blockers replace PPI in the meanwhile.


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