TITLE

Early Use of Polymyxin B Hemoperfusion in Abdominal Septic Shock

AUTHOR(S)
Cruz, Dinna N.; Antonelli, Massimo; Fumagalli, Roberto; Foltran, Francesca; Brienza, Nicola; Donati, Abele; Malcangi, Vincenzo; Petrini, Flavia; Volta, Giada; Bobbio Pallavicini, Franco M.; Rottoli, Federica; Giunta, Francesco; Ronco, Claudio
PUB. DATE
June 2009
SOURCE
JAMA: Journal of the American Medical Association;6/17/2009, Vol. 301 Issue 23, p2445
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article discusses a preliminary study which investigated the early use of polymyxin B hemoperfusion in abdominal septic shock. A prospective, multicenter, randomized controlled trial was conducted at 10 Italian tertiary care intensive care units between December 2004 and December 2007, which involved sixty-four patients with severe sepsis or septic shock who have undergone emergency surgery for intra-abdominal infection. It was found that hemodynamics and organ dysfunction were addressed by the addition of polymyxin B hemoperfusion into conventional therapy.
ACCESSION #
41689549

 

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