TITLE

Blepharokeratoconjunctivitis in Cockayne Syndrome

AUTHOR(S)
Bhojwani, Rajan; Lloyd, I. Chris; Alam, Suemyaa; Ashworth, Jane
PUB. DATE
May 2009
SOURCE
Journal of Pediatric Ophthalmology & Strabismus;May/Jun2009, Vol. 46 Issue 3, p184
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Cockayne syndrome is a multisystemic, autosontal recessive disease resulting from abnormalities of DNA repair. Ocular manifestations are common, particularly congenital cataract and retinal dystrophy, This study describes a previously unreported association of blepharokeratoconjunctivitis (BKC) in Cockayne syndrome. The authors conducted a retrospective case review of patients with Cockayne syndrome between 1997 and 2006. The ocular manifestations were documented. All cases were bilaterally aphakic from congenital cataract surgery. Four cases of BKC with resultant corneal changes were identified. Two other cases of BKC without corneal changes were also noted. There were no cases of corneal ulceration or visually significant scarring. These findings are clinically important because many patients with Cockayne syndrome wear contact lenses for the refractive correction of aphakia with a resultant risk of corneal ulceration.
ACCESSION #
41565059

 

Related Articles

  • Contact Lens Superior Limbic Keratoconjunctivitis.  // Review of Optometry;1/15/2007 Supplement, Vol. 144, p7 

    The article offers information about contact lens superior limbic keratoconjunctivitis (CLSLK), an inflammatory condition which affect the superior bulbar conjunctiva and adjacent corneal surface resulting in extensive injection and swelling. This condition will manifest with punctate staining...

  • Contact Lens-Induced Peripheral Ulcer.  // Review of Optometry;1/15/2007 Supplement, Vol. 144, p6 

    The article offers information about contact lens-induced peripheral ulcer (CLPU), a circular lesion which is composed of subepithelial and anterior stromal infiltrates with overlying epithelial defect. Patients with CLPU may complain of redness, discomfort, light sensitivity and foreign body...

  • Consider ocular surface condition before PKP. Wong, Jamie F. // Ophthalmology Times;03/15/98, Vol. 23 Issue 6, p35 

    Reports that the role of ocular surface disease in graft failure should not be underemphasized. Four cardinal principles for ocular surface disease and penetrating keratoplasty (PKP); Importance of the evaluation of ocular surface before PKP; Occurrence of persistent epithelial defects;...

  • Contact Lens-Induced Acute Red Eye Response (CLARE).  // Review of Optometry;1/15/2007 Supplement, Vol. 144, p5 

    The article offers information about contact lens-induced acute red eye response (CLARE), an inflammatory response of the cornea and conjunctiva due to a period of eyelid closure with soft contact lens wear. This response is characterized by focal and diffuse corneal infiltrates with minimal or...

  • Corneal Infiltrates in Contact Lens Wear.  // Review of Optometry;1/15/2007 Supplement, Vol. 144, p9 

    The article offers information about corneal infiltrates in contact lens wear, an inflammatory reaction of the cornea characterized by aggregates of white blood cells of the anterior stroma and epithelium. The symptoms range from being totally asymptomatic to mild to moderate irritation...

  • Corneal Neovascularization.  // Review of Optometry;1/15/2007 Supplement, Vol. 144, p9 

    The article offers information about corneal neovascularization, which refers to the ingrowth of blood vessels from the limbal vascular plexus into the cornea. The neovascularization of the cornea always represents a state of disease secondary to a variety of corneal insults. All types of...

  • Corneal Warpage.  // Review of Optometry;1/15/2007 Supplement, Vol. 144, p10 

    The article offers information on corneal warpage, a condition describing contact lens-induced changes in corneal topography. Patients with corneal warpage may experience poor vision quality in their spectacles or may develop an inability to wear contact lenses. Several signs of this condition...

  • Mucin Balls.  // Review of Optometry;1/15/2007 Supplement, Vol. 144, p17 

    The article offers information about mucin balls, which describes the glycoprotein-containing spherical collections found in the space between the corneal epithelium and contact lens. Patients with mucin balls are usually asymptomatic, and easily seen by slit-lamp biomicroscopy. In addition,...

  • Pseudodendrites.  // Review of Optometry;1/15/2007 Supplement, Vol. 144, p18 

    The article offers information about pseudodendrites, which refer to epithelial-based lesions that represent as interconnected creases covering a small area of the corneal surface. The pseudodendrites are associated with variety of clinical cases including contact lens wear and recurrent corneal...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics