Parental vitamin B[sub12] reduces hyperhomocysteinemia in end-stage renal disease

Kaplan, Ludmila N.; Mamer, Orval A.; Hoffer, L. John
February 2001
Clinical & Investigative Medicine;Feb2001, Vol. 24 Issue 1, p5
Academic Journal
Conclusions: Three monthly vitamin B[sub 12] injections modestly but distinctly reduced tHcy concentrations in hemodialysis patients whose prior vitamin B[sub 12] status was normal. Randomized placebo-controlled clinical trials of longer duration and using larger or more frequent parenteral doses are indicated to determine whether administration of this safe and inexpensive vitamin can improve hyperhomocysteinemia in ESRD.


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