TITLE

2008 - Irbesartan did not reduce all-cause death or CV hospitalization in heart failure and preserved ejection fraction

AUTHOR(S)
Ezekowitz, Justin A.; McAlister, Finlay A.
PUB. DATE
May 2009
SOURCE
ACP Journal Club;5/19/2009, Vol. 150 Issue 5, p8
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article cites a study to find out whether irbesartan reduces mortality and cardiovascular (CV) morbidity in patients with heart failure (HF) and preserved ejection fraction (PEF). The study was conducted on 4128 patients of 60 years of age with left ventricular ejection fraction. The study found that the irbesartan and placebo groups did not differ for the primary composite endpoint.
ACCESSION #
41332647

 

Related Articles

  • STUDY CONCLUSIONS AND IMPLICATIONS FOR GERIATRIC CLINICAL PRACTICE.  // Journal of Gerontological Nursing;Jan2004, Vol. 30 Issue 1, p5 

    Presents several study conclusions and their implications for geriatric clinical practice. Efficacy of Simvastatin 40 mg in reducing all-cause mortality and coronary heart disease-related death in high-risk individuals compared to placebo; Association of estrogen/progestin treatment in healthy...

  • Placebo Therapy and the Law: Prescribe with Care*. Kapp, Marshall B. // American Journal of Law & Medicine;Winter83, Vol. 8 Issue 4, p371 

    The use of placebos by physicians for therapeutic purposes is a common part of clinical medical practice. This Article examines the legal and ethical ramifications of placebo prescription. In particular, ethical concerns are related to substantive legal theories that may be advanced to attack or...

  • Erythropoietin treatment in patients with chronic heart failure: a meta-analysis. van der Meer, P.; Groenveld, H. F.; Januzzi Jr, J. L.; van Veldhuisen, D. J. // Heart;Aug2009, Vol. 95 Issue 16, p18 

    Background: Anaemia is common in patients with chronic heart failure (HF), and erythropoiesis stimulating proteins (ESPs) are frequently used for its treatment. However, recent studies in patients with malignancies and renal failure have raised concerns about the safety of these agents....

  • Long-term nitrate treatment could aid heart failure patients.  // GP: General Practitioner;2/3/2003, p14 

    Presents a study by Swedish researchers published in the 'American Heart Journal,' stating that long-term treatment with nitrates could benefit patients with chronic heart failure (CHF) and post-myocardial infarction left ventricular dysfunction (LVD). Comparison of treating patients with...

  • Methylprednisolone reduced postextubation laryngeal edema in adults with tracheal intubation.  // ACP Journal Club;Sept/Oct2007, Vol. 147 Issue 2, p48 

    The article discusses a clinical study that states that methylprednisolone reduced postextubation laryngeal edema in adults with tracheal intubation. It is stated that in adults with tracheal intubation, 12-hour pretreatment with methylprednisolone was more effective than placebo for preventing...

  • No evidence that placebos have powerful clinical effects, study says. Gottlieb, Scott // BMJ: British Medical Journal (International Edition);06/02/2001, Vol. 322 Issue 7298, p1325 

    Reports that treatment with placebo shows no evidence of having powerful clinical effects, according a study conducted at the University of Copenhagen. Reservations by many physicians toward the clinical use of placebos; Details of the study, which tested primarily the clinical effects of...

  • Effect of perioperative β blockade in patients with diabetes undergoing major non-cardiac surgery: randomised placebo controlled, blinded multicentre trial. Juul, Anne Benedicte; Wetterslev, Jørn; Gluud, Christian; Kofoed-Enevoldsen, Allan; Jensen, Gorm; Callesen, Torben; Nørgaard, Peter; Fruergaard, Kim; Bestle, Morten; Vedelsdal, Rune; Miran, André; Jacobsen, Jon; Roed, Jakob; Mortensen, Maj-Britt; Jørgensen, Lise; Jørgensen, Jørgen; Rovsing, Marie-Louise; Petersen, Pernille Lykke; Pott, Frank; Haas, Merete // BMJ: British Medical Journal (International Edition);6/24/2006, Vol. 332 Issue 7556, p1482 

    Objectives To evaluate the long term effects of perioperative β blockade on mortality and cardiac morbidity in patients with diabetes undergoing major non-cardiac surgery. Design Randomised placebo controlled and blinded multicentre trial. Analyses were by intention to treat. Setting...

  • Carvedilol: A Review of its Use in Chronic Heart Failure. Keating, Gillian M.; Jarvis, Blair // Drugs;2003, Vol. 63 Issue 16, p1697 

    Carvedilol (Dilatrend[sup ®]) blocks β[sub 1]-, β[sub 2]- and α[sub 1]-adrenoceptors, and has antioxidant and antiproliferative effects. Carvedilol improved left ventricular ejection fraction (LVEF) in patients with chronic heart failure (CHF) in numerous studies. Moreover,...

  • Acupuncture improves exercise tolerance of patients with heart failure: a placebo-controlled pilot study. Kristen, Arnt V.; Schuhmacher, Boris; Strych, Kathrin; Lossnitzer, Dirk; Friederich, Hans-Christoph; Hilbel, Thomas; Haass, Markus; Katus, Hugo A.; Schneider, Antonius; Streitberger, Konrad M.; Backs, Johannes // Heart;Sep2010, Vol. 96 Issue 17, p1396 

    Background Congestive heart failure (CHF) is a complex clinical syndrome with autonomic dysbalance and increased plasma levels of inflammatory cytokines, which further worsen the syndrome. Experimental data have shown that stimulation of certain acupoints decreases autonomic dysbalance....

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics