2009 - Review: Evidence is insufficient to evaluate effectiveness of antiviral therapies for chronic hepatitis B

Reichen, J.
May 2009
ACP Journal Club;5/19/2009, Vol. 150 Issue 5, p4
Academic Journal
The article discusses studies which were conducted to find out whether antiviral therapy is effective in patients with chronic hepatitis B infection. Meta-analysis showed that entecavir and lamivudine did not differ for death or hepatic decompensation. Individual RCTs showed that antiviral drugs did not differ from placebo. The studies concluded that there is a lack of evidence to evaluate effectiveness of antiviral therapies for chronic hepatitis B.


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