2009 - What kind of randomized trials do patients and clinicians need?
- What kind of randomised trials do patients and clinicians need? Zwarenstein, Merrick; Treweek, Shaun // Evidence Based Medicine;Aug2009, Vol. 14 Issue 4, p101
The article offers information on the kinds of randomised controlled trials (RCTs). Daniel Schwartz and Joseph Lellouch argues that there are two kinds of randomised trials in different attituted to evaluate treatment. They are the pragmatic and explanatory, which require different approaches to...
- Clinical Trials (Book Review). Gore, Sheila M. // British Medical Journal (Clinical Research Edition);2/7/1981, Vol. 282 Issue 6262, p467
Reviews the book 'Clinical Trials,' by Daniel Schwartz, Robert Flamant and Joseph Lellouch and translated by M.J.R. Healy.
- Screening is effective in early detection of ovarian cancer. Wise, Jacqui // BMJ: British Medical Journal (Overseas & Retired Doctors Edition;3/21/2009, p683
The article reports on the results of a large randomized controlled clinical trial in Great Britain called the U.K. Collaborative Trial of Ovarian Cancer Screening, which was conducted in an effort to determine the effectiveness of medical screening for ovarian cancer. The trial found that...
- Protocol for the PINCER trial: a cluster randomised trial comparing the effectiveness of a pharmacist-led IT-based intervention with simple feedback in reducing rates of clinically important errors in medicines management in general practices. Avery, Anthony J.; Rodgers, Sarah; Cantrill, Judith A.; Armstrong, Sarah; Elliott, Rachel; Howard, Rachel; Kendrick, Denise; Morris, Caroline J.; Murray, Scott A.; Prescott, Robin J.; Cresswell, Kathrin; Sheikh, Aziz // Trials;2009, Vol. 10, p1
Background: Medication errors are an important cause of morbidity and mortality in primary care. The aims of this study are to determine the effectiveness, cost effectiveness and acceptability of a pharmacist-led information-technology-based complex intervention compared with simple feedback in...
- Varieties of Standard-of-Care Treatment Randomized Trials. Kim, Scott Y. H.; Miller, Franklin G. // JAMA: Journal of the American Medical Association;3/3/2015, Vol. 313 Issue 9, p895
The authors explore the ethical aspects of standard-of-care treatment randomized clinical trials (RCT). They discuss the factors that make it difficult to assess the ethics of standard-of-care-treatment RCTs, the factors that affect risk-benefit assessment and informed consent in RCTs and the...
- Dichotomization of Primary Outcomes Serves External Validity. Dupuy, Alain; Nassar, Dany // Journal of Investigative Dermatology;Jan2014, Vol. 134 Issue 1, p267
A letter to the editor is presented in response to the article "Binary outcomes are not better than continuous variables in randomized controlled trials" by J. Kottner and D. Streiner, that was publised in a 2013 issue of the journal.
- Randomised controlled trials. Geddes, John // British Journal of Psychiatry;Jul2014, Vol. 205 Issue 1, p43
A definition of randomised controlled trials is presented.
- Importance of Blinding in Randomized Trials. Strite, Sheri A.; Stuart, Michael E.; Psaty, Bruce M.; Prentice, Ross L. // JAMA: Journal of the American Medical Association;11/17/2010, Vol. 304 Issue 19, p2127
A letter to the editor is presented in response to the article "Minimizing bias in randomized trials: The importance of blinding," by B. M. Patsy and R. L. Prentice published in the volume 304, issue 7 of the "Journal of the American Medical Association" and a response from the authors.
- Clinical research evidence of cupping therapy in China: a systematic literature review. Huijuan Cao; Mei Han; Xun Li; Shangjuan Dong; Yongmei Shang; Qian Wang; Shu Xu; Jianping Liu // BMC Complementary & Alternative Medicine;2010, Vol. 10, p70
Background: Though cupping therapy has been used in China for thousands of years, there has been no systematic summary of clinical research on it. This review is to evaluate the therapeutic effect of cupping therapy using evidence-based approach based on all available clinical studies. Methods:...