2009 - What kind of randomized trials do patients and clinicians need?

Zwarenstein, Merrick; Treweek, Shaun
May 2009
ACP Journal Club;5/19/2009, Vol. 150 Issue 5, p1
Academic Journal
The article cites several studies on randomized controlled trials (RCTs). A study conducted in 1967 by researchers Daniel Schwartz and Joseph Lellouch which stated that there are 2 kinds of RCTs, which embody radically different attitudes to evaluation of treatment. They named these trials pragmatic and explanatory and asserted that these 2 attitudes require different approaches to the design of a randomized trial.


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