TITLE

Significant reduction of air microbubbles with the dynamic bubble trap during cardiopulmonary bypass

AUTHOR(S)
Schönburg, M.; Urbanek, P.; Erhardt, G.; Kraus, B.; Taborski, U.; Mühling, A.; Hein, S.; Roth, M.; Tiedtke, H.; Klövekorn, W.
PUB. DATE
January 2001
SOURCE
Perfusion;Jan2001, Vol. 16 Issue 1, p19
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Air microbubbles mostly occur unnoticed during cardiopulmonary bypass and are predominantly responsible for serious postoperative psycho-neurological dysfunction. A dynamic bubble trap (DBT), which removes air microbubbles from the arterial blood, was tested in a clinical study. The aim was to evaluate the efficiency of microbubble removal under clinical conditions. As blood passes through the DBT, which is placed in the arterial line between the arterial filter and arterial cannula, it is converted into a rotating stream. The bubbles are directed to the centre of the blood flow and are collected in the distal end of the DBT, from where they are returned to the cardiotomy reservoir. Doppler ultrasonography was used to detect the microbubbles before and after the DBT, and also the number of high-intensity transient signals (HITS) in the right and left middle cerebral artery during extracorporeal circulation. A significant reduction of microbubbles in the arterial line (3990 before DBT, 537 after, p < 0.001) and HITS in the brain (51 in the DBT group, 77 in the placebo group, p = 0.04) was measured.
ACCESSION #
4124485

 

Related Articles

  • Effect of cardiopulmonary bypass on cortical cerebral oxygenation during coronary artery bypass grafting Talpahewa, Sudath P.; Lovell, A. Timothy; Angelini, Gianni D.; Ascione, Raimondo // European Journal of Cardio-Thoracic Surgery;Oct2004, Vol. 26 Issue 4, p676 

    Objective: To investigate the changes in cerebral oxygenation during coronary artery bypass grafting (CABG) with normothermic cardiopulmonary bypass (CPB) using near infrared spectroscopy. Methods: Measurement of cerebral cortical oxygenation changes included concentration of deoxygenated...

  • Editorial. Taylor, K. // Perfusion;1999, Vol. 14 Issue 5, p319 

    Editorial. Discusses the introduction of computer control systems into the cardio-pulmonary bypass circuit; Views on mathematical modelling of extracorporeal circulation; Evolution of automated control systems.

  • An update on perfusion safety: does the type of perfusion practice affect the rate of incidents related to cardiopulmonary bypass? Stammers, A.H.; Mejak, B.L. // Perfusion;May2001, Vol. 16 Issue 3, p189 

    Cardiopulmonary bypass (CPB) techniques vary among adult and pediatric patients undergoing cardiac surgery. This may result in a differential conduct of CPB between various aged patients. The present study reports on perfusion incidents occurring in hospitals using extracorporeal circulation. An...

  • Vacuum-assisted venous return in pediatric cardiopulmonary bypass. Berryessa, R.; Wiencek, R.; Jacobson, J.; Hollingshead, D.; Farmer, K.; Cahill, G. // Perfusion;Jan2000, Vol. 15 Issue 1, p63 

    Vacuum-assisted venous return (VAVR) has been reported to offer benefits for adults undergoing cardiopulmonary bypass (CPB), such as improved venous return, lowering priming volume (by eliminating the need to prime the venous line), and the use of smaller venous cannulae. All these benefits...

  • Affinity pump system: a new peristaltic blood pump for cardiopulmonary bypass. Jaggy, C.; Lachat, M.; Leskosek, B.; Zünd, G.; Turina, M. // Perfusion;Jan2000, Vol. 15 Issue 1, p77 

    An in vitro study has been carried out to assess the pump performance of a new peristaltic, extracorporeal displacement pump (Affinity) for cardiopulmonary bypass. The pump system consists of a pump rotor (0--110 rpm), a pump chamber, a venous reservoir with a 5/8 connecting tube and the...

  • Carotid shunt provides cerebral protection during emergency coronary artery bypass grafting in a patient with bilateral high grade carotid stenosis: a case report. Bellos, John K.; Kogerakis, Nektarios; Kiriazis, Charalampos; Gougoulakis, Alexandros; Panagiotou, Matthew // Journal of Cardiothoracic Surgery;2011, Vol. 6 Issue 1, p33 

    Background: Management of patients with co-existent coronary and carotid disease is a controversial and challenging issue. The risk for stroke after coronary artery bypass grafting (CABG) in patients with hemodynamically significant carotid stenosis is up to 30%. In these patients a common...

  • Inflammatory Response in Patients under Coronary Artery Bypass Grafting Surgery and Clinical Implications: A Review of the Relevance of Dexmedetomidine Use. Heinzmann Bulow, Neusa Maria; Colpo, Elisângela; Duarte, Marta Frescura; Mafassioly Correa, Eduardo Francisco; Schlosser, Rochelle Silveira; Lauda, Anelise; Kade, Ige Joseph; Teixeira Rocha, João Batista // ISRN Otolaryngology;2014, p1 

    Despite the fact that coronary artery bypass grafting surgery (CABG) with cardiopulmonary bypass (CPB) prolongs life and reduces symptoms in patients with severe coronary artery diseases, these benefits are accompanied by increased risks. Morbidity associated with cardiopulmonary bypass can be...

  • Association between early and three month cognitive outcome after off-pump and on-pump coronary bypass surgery. van Dijk, D.; Moons, K. G. M.; Keizer, A. M. A.; Jansen, E. W. L.; Hijman, R.; Diephuis, J. C.; Borst, C.; de Jaegere, P. P. T.; Grobbee, D. E.; Kalkman, C. J. // Heart;Apr2004, Vol. 90 Issue 4, p431 

    Objective: To describe the association between cognitive outcome in the first postoperative week and that at three months after both off-pump and on-pump coronary bypass surgery, and to make a direct comparison of early cognitive outcome after off-pump versus on-pump surgery. Design: Randomised...

  • Lepirudin as an alternative to "heparin allergy" during cardiopulmonary bypass. Parissis, Haralabos // Journal of Cardiothoracic Surgery;2011, Vol. 6 Issue 1, p44 

    A treatment strategy of a difficult and unusual problem is presented. We are reporting a case of a patient who had a documented allergy to heparin and required Cardiac surgery for an ASD closure. The anticoagulation regime used during cardiopulmonary bypass was lepirudin based. This report...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics