Breast cancer: genetics

Eccles, Diana
December 2008
Menopause International;Dec2008, Vol. 14 Issue 4, p183
Academic Journal
The article delves into the heritable risk of breast cancer. It states that BRCA1 and BRCA2 are the dominantly inherited breast cancer predisposition genes and can also contribute to the risk of developing ovarian cancer. Managing a high-risk gene carrier involves applying bilateral salpingo-oophorectomy often before the natural menopause which induces an early surgical menopause. However, it is noted that BRCA1 and BRCA2 gene mutations account for only a small proportion of all breast cancers.


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