Obesity and arthritis

Magliano, Malgorzata
December 2008
Menopause International;Dec2008, Vol. 14 Issue 4, p149
Academic Journal
Obesity affects over 20% of the UK's adult population and its prevalence is rising. Obesity can lead to a variety of musculoskeletal problems and is independently associated with locomotor disability and joint pain. Obesity increases the risk of radiographic knee osteoarthritis (OA), but has a lesser effect on disease progression. The association with hip and hand OA is weaker, but implies that excess adipose tissue produces humoral factors, altering articular cartilage metabolism. It has been postulated that the leptin system could be a link between metabolic abnormalities in obesity and increased risk of OA. Although obesity was initially thought to increase the risk of rheumatoid arthritis (RA), further studies showed, that heavier patients with RA have less radiological disease progression and possibly better survival. On the other hand, obesity is strongly associated with hypeuricaemia and gouty arthritis. High body weight correlates independently with metabolic syndrome and may contribute to increased cardiovascular morbidity in patients with gout. Weight reduction should be an important part of treatment for OA and gout. Because obesity at a young age correlates with the development of OA and gout in later life, preventive public health strategies aimed at lowering the incidence of obesity are of most importance.


Related Articles

  • Burden of Rheumatic Diseases in A Rural Community of Bangladesh. AHMED, MONIRUZZAMAN; ATIQUL HAQ, SYED; ISLAM, MD. NAZRUL; KRISNA BANIK, SREE; NOOR ALAM, MOHAMMAD // Journal of Medicine;2014, Vol. 15 Issue 2, p125 

    Objective: To estimate the magnitude, burden of illness and help-seeking behavior of patients with musculoskeletal complaints and to provide incidence of osteoarthritis, low back pain, fibromyalgia, rheumatoid arthritis, gout, and other inflammatory and non-inflammatory rheumatic diseases in a...

  • Rheumatology. Madhok, Rajan; Kerr, Hilary // BMJ: British Medical Journal (International Edition);10/07/2000, Vol. 321 Issue 7265, p882 

    Presents an overview of advances in rheumatology and the treatment and prevention of musculoskeletal diseases as of October 2000. Impact of diet and physical activity on the symptoms of osteoarthritis; Effectiveness of gastroprotective and cyclo-oxygenase-2 selective drugs in reducing the...

  • Musculoskeletal problems plague millions. Menehan, Karen // Massage Magazine;Mar/Apr2004, Issue 108, p30 

    Discusses findings of a report about musculoskeletal disorders in released by the World Health Organization and the Bone and Joint Decade Initiative. Need to fund preventive and treatment options; Osteoarthritis; Rheumatoid arthritis; Low-back pain; Bone fractures.

  • Towards an ICF Core Set for chronic musculoskeletal conditions: commonalities across ICF Core Sets for osteoarthritis, rheumatoid arthritis, osteoporosis, low back pain and chronic widespread pain. Schwarzkopf, S. R.; Ewert, T.; Dreinhöfer, K. E.; Cieza, A.; Stucki, G. // Clinical Rheumatology;Nov2008, Vol. 27 Issue 11, p1355 

    The objective of the study was to identify commonalities among the International Classification of Functioning, Disability and Health (ICF) Core Sets of osteoarthritis (OA), osteoporosis (OP), low back pain (LBP), rheumatoid arthritis (RA) and chronic widespread pain (CWP). The aim is to...

  • The Many Faces of Arthritis.  // Nutrition Health Review: The Consumer's Medical Journal;2013, Issue 109, p12 

    The article focuses on various types of arthritis including osteoarthritis, rheumatoid arthritis and juvenile rheumatoid arthritis.

  • Cognitive Behavioral Therapy for Patient With Rheumatoid Arthritis and Obesity. de Oliveira Ribeiro, Natalia Pinho; de Mello Schier, Alexandre Rafael; Marinho, Tamires; Machado, Sergio; Nardi, Antonio Egidio; Silva, Adriana Cardoso // Journal of Medical Cases;2013, Vol. 4 Issue 7, p443 

    Rheumatoid arthritis is an autoimmune disease that causes physical and psychological symptoms when patients are not monitored; these symptoms include depression, anxiety and even the risk of suicide. This study is a case report of one female patient who has Rheumatoid arthritis, and obesity. The...

  • SECTION 8 MUSCULOSKELETAL DISORDERS.  // Nurse Practitioners Prescribing Reference;Fall2012, Vol. 19 Issue 3, p152 

    The article provides usage information such as indications, warnings and adverse reactions on various drugs for musculoskeletal disorders Actemra from Genentech for rheumatoid arthritis (RA), Actonel from Warner Chilcott for postmenopausal osteoporosis, and Uloric from Takeda for hyperuricemia...

  • SECTION 8 MUSCULOSKELETAL DISORDERS.  // MPR - Pharmacist's Edition;Fall2014, Vol. 8 Issue 3, p133 

    The article offers information on several drugs for the treatment of musculoskeletal disorders. The Advil pain reliever from healthcare company Pfizer Consumer Healthcare is indicated for the treatment of minor arthritic pain. The indications of the Daypro non-steroidal anti-inflammatory drug...

  • Use of 99mTc-anti-CD3 scintigraphy in the differential diagnosis of rheumatic diseases. Lobo Lopes, Flávia Paiva Proença; Leitão de Azevedo, Mário Newton; Marchiori, Edson; Barbosa da Fonseca, Lea Mirian; Lopes de Souza, Sergio Augusto; Gutfilen, Bianca // Rheumatology;May2010, Vol. 49 Issue 5, p933 

    Objectives. The aim of this study was to assess the use of anti-CD3, labelled with technetium-99m scintigraphy, for evaluating the joints of patients with RA, juvenile idiopathic arthritis (JIA), OA and gouty arthritis, and to establish the diagnosis parameters for each disease.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics