Perceived Health Status of Women with Overt and Subclinical Hypothyroidism

Vigário, Patrícia; Teixeira, Patrícia; Reuters, Vaneska; Almeida, Cloyra; Maia, Maicon; Silva, Marina; Vaisman, Mário
June 2009
Medical Principles & Practice;Jun2009, Vol. 18 Issue 4, p317
Academic Journal
Objective: The objective of this study was to investigate the health status of women with overt and subclinical hypothyroidism and relate it to the presence of clinical signs and symptoms of the disease. Subjects and Methods: A cross-sectional study was conducted on 232 women divided into 3 groups: overt hypothyroidism (n = 14); subclinical hypothyroidism (n = 152), and controls (n = 66). Health status was evaluated by the questionnaire SF-36, and the clinical signs and symptoms of hypothyroidism were assessed with the Billewicz scale modified by Zulewski. The Kruskal-Wallis test followed by the Mann-Whitney U test with Bonferroni correction was applied to compare continuous variables between the groups. To assess the relationship between SF-36 domains and the clinical score, as well as SF-36 domains and serum thyroid-stimulating hormone levels, the Spearman correlation coefficient was calculated. Results: Patients with overt hypothyroidism presented systematically lower scores in all SF-36 domains (p < 0.05), both in relation to subclinical hypothyroidism patients and controls. This indicates a great dissatisfaction with health status in this group. Patients with subclinical hypothyroidism presented statistically lower scores in relation to controls with the exception of the role-emotional and bodily pain domains, where although they were not statistically significant, scores were clinically different. Highly negative correlations between SF-36 domains and the clinical score were observed in overt hypothyroidism (physical function r = –0.80, p < 0.01; bodily pain r = –0.74, p < 0.01). Conclusion: Overt hypothyroidism seemed to be associated with worse perception of health status, negatively associated with clinical score. Copyright © 2009 S. Karger AG, Basel


Related Articles

  • Required muscle mass for preventing lifestyle-related diseases in Japanese women. Miyatani, Masae; Kawano, Hiroshi; Masani, Kei; Gando, Yuko; Yamamoto, Kenta; Tanimoto, Michiya; Oh, Taewoong; Usui, Chiyoko; Sanada, Kiyoshi; Higuchi, Mitsuru; Tabata, Izumi; Miyachi, Motohiko // BMC Public Health;2008, Vol. 8 Issue 1, p291 

    Background: Since it is essential to maintain a high level of cardiorespiratory fitness to prevent life-style related disease, the Ministry of Health, Labour and Welfare of Japan in 2006 proposed to determine the maximal oxygen uptake (Vo2max: mL·kg-1·min-1) reference values to prevent...

  • Urban women's socioeconomic status, health service needs and utilization in the four weeks after postpartum hospital discharge: findings of a Canadian cross-sectional survey. Landy, Christine Kurtz; Sword, Wendy; Ciliska, Donna // BMC Health Services Research;2008, Vol. 8, Special section p1 

    Background: Postpartum women who experience socioeconomic disadvantage are at higher risk for poor health outcomes than more advantaged postpartum women, and may benefit from access to community based postpartum health services. This study examined socioeconomically disadvantaged (SED)...

  • Editorial: The Perinatal Paradox. Leviton, Alan // American Journal of Public Health;Jul1995, Vol. 85 Issue 7, p906 

    The article highlights the "perinatal paradox" and the incongruity between the superb ability to care for the individual patient and the dismal failure to address the problems of the larger society. It is agreed that the problems of the larger society has not been adequately addressed. It is...

  • Effect of low-intensity back exercise on quality of life and back extensor strength in patients with osteoporosis: a randomized controlled trial. Hongo, M.; Itoi, E.; Sinaki, M.; Miyakoshi, N.; Shimada, Y.; Maekawa, S.; Okada, K.; Mizutani, Y. // Osteoporosis International;Oct2007, Vol. 18 Issue 10, p1389 

    Randomized controlled study in 80 postmenopausal women with osteoporosis was conducted to investigate the effect of a home-based, simple, low-intensity exercise. Low-intensity back-strengthening exercise was effective in improving the quality of life and back extensor strength....

  • Changes in health-related quality of life following imprisonment in 92 women in England: a three month follow-up study. Plugge, Emma; Douglas, Nick; Fitzpatrick, Ray // International Journal for Equity in Health;2011, Vol. 10 Issue 1, p21 

    Background: Despite the considerable changes in the provision of health care to prisoners in the UK there is little published literature that attempts to examine broader aspects of health and the impact of imprisonment on these, focusing instead on disease specific areas. This is surprising...

  • The impact of urinary incontinence on self-efficacy and quality of life. Shelton Broome, Barbara Ann // Health & Quality of Life Outcomes;2003, Vol. 1, p35 

    Urinary incontinence impacts 15 to 35% of the adult ambulatory population. Men after the removal of the prostate for cancer can experience incontinence for several weeks to years after the surgery. Women experience incontinence related to many factors including childbirth, menopause and surgery....

  • WOMEN DRUNKARD: They are growing. Valyan, Prempal Singh // Woman's Era;Jun2017, Vol. 44 Issue 1045, p109 

    The article presents the author's views regarding the increased number of women drunkards. Topics included are the social life of the workers in the modelling industry, several disorders in women associated with the consumption of alcohol reported by the World Health Organisation, and the...

  • Maybe You're Not Just Tired. Lumiere, Erica // Parents;Sep2003, Vol. 78 Issue 9, p113 

    Provides information on thyroid disorders among new mothers. Symptoms of hypothyroidism; Risk of thyroid disorders among women; Connection of thyroid disorder with pregnancy. INSETS: Getting Tested;Postbaby Problems.

  • The health and economic benefits of reducing intimate partner violence: an Australian example. Cadilhac, Dominique A.; Sheppard, Lauren; Cumming, Toby B.; Thayabaranathan, Tharshanah; Pearce, Dora C.; Carter, Rob; Magnus, Anne // BMC Public Health;Jul2015, Vol. 15 Issue 1, p1 

    Background: Intimate partner violence (IPV) has important impacts on the health of women in society. Our aim was to estimate the health and economic benefits of reducing the prevalence of IPV in the 2008 Australian female adult population. Methods: Simulation models were developed to show the...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics