Early amino acids and the metabolic response of ELBW infants (1000 g) in three time periods

Radmacher, P. G.; Lewis, S. L.; Adamkin, D. H.
June 2009
Journal of Perinatology;Jun2009, Vol. 29 Issue 6, p433
Academic Journal
Objective:To evaluate early amino-acid (AA) administration in extremely low birth weight (ELBW) infants over three time periods, beginning with the initiation of this strategy.Study design:This was a retrospective study of ELBW infants between 2000 and 2007. Nutritional intake and laboratory results were monitored during the first 5 days of life. Growth rates and complications were followed until discharge.Result:Infants were similar in birth weight (BW), gestational age (GA) and severity of illness. The age at initiation of AA decreased significantly over time. Age at weight nadir, return to BW and percent postnatal weight loss decreased in epoch 3. There were modest increases in blood urea nitrogen (BUN), but no significant metabolic disturbances were observed. Cholestasis was more prevalent in epoch 2.Conclusion:AA administration within the first hours of life appears to be safe and beneficial for ELBW infants. Absent signs of renal dysfunction, a modest rise in BUN is consistent with the neonate's utilization of AAs for energy.Journal of Perinatology (2009) 29, 433–437; doi:10.1038/jp.2009.36; published online 2 April 2009


Related Articles

  • Intrahepatic cholestasis of pregnancy may lead to low birth weight. UYAR, İbrahim; GÜLHAN, İbrahim; ÖZTEKİN, Deniz; GEZER, Cenk; EKİN, Atalay; KURTULMUŞ, Seçil KARACA; ÖZEREN, Mehmet // Turkish Journal of Medical Sciences;2015, Vol. 45 Issue 3, p723 

    Background/aim: To evaluate patients hospitalized in our clinic in the last 5 years with the diagnosis of intrahepatic cholestasis of pregnancy (ICP). Materials and methods: One hundred and fifty patients hospitalized with a diagnosis of ICP between January 2008 and May 2013 were evaluated...

  • Dopamine infusion and hypothyroxinaemia in very low birth weight preterm infants. Filippi, Luca; Cecchi, Alessandra; Tronchin, Michele; Dani, Carlo; Pezzati, Marco; Seminara, Salvatore; Gasperini, Serena; Zammarchi, Enrico; Rubaltelli, Firmino F. // European Journal of Pediatrics;2004, Vol. 163 Issue 1, p7 

    Unlabelled: The purpose of this study was to assess the relationship between transient hypothyroxinaemia of prematurity (THOP) in very low birth weight newborns and dopamine administration. A total of 172 newborns was enrolled in a prospective observational study and divided into...

  • SPLANCHNIC CIRCULATION IN SMALL FOR DATE NEWBORNS. Paulusova, E.; Stillova, L.; Haskova, K.; Matasova, K. // Acta Medica Martiniana;Nov2012, Vol. 12 Issue 3, p5 

    Hypotrophic newborn is a newborn with birth weight below the 5th percentile weight of corresponding gestational age. Hypotrophic infants have higher morbidity and mortality in comparison with eutrophic neonates. A higher incidence of hypoglycemia, polycythemia, hyperbilirubinemia,...

  • Morbilidad neonatal en un hospital de segundo nivel de atención. Plaza-García, Margarita; Álvarez Romero, Claudia Teresa // Revista Mexicana de Pediatria;May/Jun2013, Vol. 80 Issue 3, p93 

    Objective: Know the causes of admission to the neonatology service of the hospital. Material and methods: We reviewed the clinical records of neonates admitted for 18 months and information was obtained from the causes of admission of children. Results: Were admitted 243 newborns, 56.8% were of...

  • VENTILATION ASSOCIATED PNEUMONIA IN LOW BIRTH WEIGHT NEWBORNS. Olariu^, Gabriela; Icma, Daniela; Olariu, Laura; Olariu, S. // Acta Medica Transilvanica;jun2011, Vol. 16 Issue 2, p242 

    Ventilation associated pneumonia (VAP) is a nosocomial pneumonia occurring after 48 hours of mechanical ventilation. VAP incidence is between 5-40%. We aimed to identify the risk factors associated with VAP in premature infants below 32 weeks gestation and to implement a project to improve...

  • Diaphragmatic paralysis among very low birth weight infants following ligation for patent ductus arteriosus. Hsu, Kai-Hsiang; Chiang, Ming-Chou; Lien, Reyin; Chu, Jaw-Ji; Chang, Yu-Sheng; Chu, Shih-Ming; Wong, Kin-Sun; Yang, Peng-Hong // European Journal of Pediatrics;Nov2012, Vol. 171 Issue 11, p1639 

    Management of diaphragmatic paralysis (DP) among newborn infants remains controversial, especially for very low birth weight (VLBW) infants following ligation for patent ductus arteriosus (PDA). This study aimed to characterize the impact of DP after PDA ligation among VLBW infants. Clinical...

  • Healthy Start Program and Feto-Infant Morbidity Outcomes: Evaluation of Program Effectiveness. Salihu, Hamisu M.; Mbah, Alfred K.; Jeffers, Delores; Alio, Amina P.; Berry, Lo // Maternal & Child Health Journal;Jan2009, Vol. 13 Issue 1, p56 

    Objective We evaluate the impact of the Healthy Start intervention program on feto-infant morbidity within a community setting. Methods Prospective data from 2002 to 2007 within the ongoing Federally funded Healthy Start intervention project in Central Hillsborough County were merged with...

  • Necrotizing Enterocolitis in Very Low BirthWeight Infants: A Systemic Review. Patel, Bhoomika K.; Shah, Jigna S. // ISRN Gastroenterology;2012, p1 

    Necrotizing enterocolitis (NEC) is the most common serious gastrointestinal disorder affecting very preterm or very low birth weight infants. The risk is inversely proportional to gestational age and weight at birth. Fetal growth restriction and compromise may be additional specific risk...

  • A Female Advantage? Danner, Valerie // Access;Jan2001, Vol. 15 Issue 1, p12 

    Reports the risk of illness in newborn boys in the United States. Difficulty of male premature infants in breathing; Complications of low birth weights and prematures; Comparison between female and male infants on health aspects.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics