Ruiz-Botero, Felipe; Pachajoa, Harry; Saldarriaga, Wilmar; Isaza, Carolina
January 2009
Revista Colombiana de Obstetricia y Ginecologia;2009, Vol. 60 Issue 1, p79
Academic Journal
Arthrogryposis multiplex congenita (AMC) is a group of rarely occurring musculoskeletal disorders, characterised by multiple joint contractures affecting the muscles of the upper and lower limbs and the back. This condition's aetiology remains unknown and many causal agents have been implicated, particularly viral infections and intra-uterine restrictive conditions. Objective: contributing a case of AMC in a monochorionic biamniotic twin pregnancy to the literature and reviewing this congenital malformation's aetiology and physiopathogeny. Case presentation: a second-born male twin, weighing 1345 gr, shortening of the four limbs in all segments was observed, accompanied by joint contractures leading to marked hand and foot deviation towards the mid line and the impossibility of active movement. Discussion: AMC being displayed in one of the identical twins mentioned in the present report suggests that this condition did not take place because of chromosomal alteration or a hereditary disease. Rather, it was presented because of one or several external factors (probably mechanical) affecting the foetus which may have jeopardised the normal development of the joints and led to AMC appearing. This is the fourth report of similar characteristics in the literature reviewed.


Related Articles

  • From the Editor-in-Chief. Anderson, Robert H.; Franklin, Rodney C. G.; Béland, Marie J.; Krogmann, Otto N. // Cardiology in the Young;Apr2006, Vol. 16 Issue 2, p105 

    The article summarizes a report pertaining to the creation of a standardized system for describing the malformation found in neonates, infants, children and adults with congenital disease. The article describes the efforts exerted by the International Society for Nomenclature of Paediatric and...

  • Síndrome de Escobar o pterygium múltiple congénito. Reporte de un caso. Camacho Franco, Luis Alberto; Nualart, Luis; Leonori, Román Capdevila // Acta Ortopedica Mexicana;sep/oct2006, Vol. 20 Issue 5, p214 

    Multiple pterygium syndrome was first described by Bussière in 1902; in 1978 Víctor Escobar described fully this syndrome, which is currently known as Escobar syndrome. It is an autosomal recessive disorder whose pathophysiology is still unknown. The following entities should be considered...

  • Congenital biliary dilatation in dizygotic twins. Tokuhara, Katsuji; Hamada, Yoshinori; Yui, Rintaro; Tanano, Akihide; Takada, Kohei; Kamiyama, Yasuo // Pediatric Surgery International;Jan2005, Vol. 21 Issue 1, p17 

    Congenital biliary dilatation (CBD) of different types was recently noted in dizygotic twins. Our cases suggest the possibility of hereditary involvement in CBD. On the other hand, CBD discordance in six sets of monozygotic twins has been reported, which would suggest that the occurrence of CBD...

  • Surgical repair of a vesicovaginal fistula guided by a black braided silk suture line.  // International Urogynecology Journal;Nov2008, Vol. 19 Issue 11, p1577 

    Abstract  The purpose of the study was to evaluate the effect of the identification of the margins of a vesicovaginal fistula (VVF) during its repair by passing a black braided silk suture line through the fistula. During the repair of a VVF, a suture line was placed through the fistula....

  • Familial Aggregation of Hypospadias: A Cohort Study. Tine H. Schnack; Slobodan Zdravkovic; Charlotte Myrup; Tine Westergaard; Kaare Christensen; Jan Wohlfahrt; Mads Melbye // American Journal of Epidemiology;Feb2008, Vol. 167 Issue 3, p251 

    Hypospadias is one of the most common birth defects. However, its etiology remains largely unknown. The authors investigated the contribution of genetic and environmental factors to familial aggregation of hypospadias. Using Danish health registers, they identified 5,380 boys diagnosed with...

  • Genetic Disorders and Ethnicity. Bar-Yam, Naomi Bromberg // International Journal of Childbirth Education;Dec2000, Vol. 15 Issue 4, p19 

    Analyzes the connection of genetic disorders with ethnicity. Number of babies born in the U.S. each year with birth defects; Cause of genetic disorders; Role of ethnicity in the occurrence of genetic disorders in certain groups; Methods to detect and prevent genetic disorders; List of...

  • Antley Bixler Syndrome With Prenatal Imaging.  // Journal of Medical Genetics;Sep2004 Supplement, Vol. 41, pS38 

    Presents an abstract of the study entitled "Antley Bixler Syndrome With Prenatal Imaging," by Elizabeth Sweeney, R. Day and L. Bricker, presented during the British Human Genetics Conference held at the University of York in England from September 13 to 15, 2004.

  • Ocular malformations, postaxial polydactyly, and delayed intramembranous ossification: a new autosomal dominant condition. Martin, Donna M.; Gorski, Jerome L. // Journal of Medical Genetics;Aug2001, Vol. 38 Issue 8, p547 

    Reports that microphthalmia and related ocular abnormalities are a common component of many multiple congenital anomaly syndromes. Case discussions; Autosomal dominant conditions.

  • An intrarenal supernumerary ovary concurrent with a completely duplicated pelvis and ureter. Zhao Zhigang; Shen Wenlu // International Urogynecology Journal;Oct2007, Vol. 18 Issue 10, p1243 

    Abstract  An intrarenal supernumerary ovary is particularly rare. To the best of our knowledge, only two cases have been documented so far, all reported without other congenital malformations. In this case report, we present the first case of this lesion, which is concurrent with a...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics