TITLE

Variability of SCC mec in the Zurich area

AUTHOR(S)
Ender, M.; Burger, S.; Sokoli, A.; Zbinden, R.; Berger-Bächi, B.; Heusser, R.; Senn, M. M.; McCallum, N.
PUB. DATE
June 2009
SOURCE
European Journal of Clinical Microbiology & Infectious Diseases;Jun2009, Vol. 28 Issue 6, p647
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
A periodic survey of methicillin-resistant Staphylococcus aureus (MRSA) in Zurich in 2004 and 2006 revealed a consistently low prevalence of MRSA. SCC mec and ccr typing showed fluctuations in the proportions of SCC mec types and in the carriage of mobile virulence determinants. Together with the presence of variant SCC mecs these findings suggest a high clonal diversity and level of SCC mec recombination. The prevalence of a local “drug clone", associated with low-level methicillin resistance and rapid growth, significantly decreased. This clone had spread among intraveneous drug users, steadily increasing from 1994 to 2001 and was dominant in 2001. Apparently, changes in the management of the Zurich drug scene have restricted the spread of this clone.
ACCESSION #
40114734

 

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