TITLE

Outcome after coronary artery bypass surgery with miniaturized versus conventional cardiopulmonary bypass

AUTHOR(S)
Rimpiläinen, R.; Biancari, F.; Wistbacka, J. O.; Loponen, P.; Koivisto, S. P.; Rimpiläinen, J.; Teittinen, K.; Nissinen, J.
PUB. DATE
November 2008
SOURCE
Perfusion;Nov2008, Vol. 23 Issue 6, p361
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We have reviewed the results of our experience with the use of miniaturized (Mini-CPB) versus conventional (C-CPB) cardiopulmonary bypass in coronary artery bypass surgery (CABG). This study included 365 patients who underwent CABG with C-CPB and 101 patients with Mini-CPB. In-hospital mortality was lower in the C-CPB group (1.4% vs. 3.0%, P = 0.38). A better, but not statistically significant, immediate outcome was observed in the C-CPB group as indicated by a shorter length of stay in the intensive care unit as well as a lower incidence of combined adverse end-point. However, this was probably due to significantly higher operative risk in the Mini- CPB group (logistic EuroSCORE: 8.5 ± 10.0 vs. 4.6 ± 7.1, P < 0.0001). Seventy-seven propensity score-matched pairs had similar immediate postoperative results after Mini-CPB and C-CPB (30-day mortality: 1.3% vs. 1.3%; stroke: 0% vs. 0%; intensive care unit stay ≥5 days: 6.5% vs. 9.1%; combined adverse events: 14.3% vs. 11.7%). Mini-CPB achieves similar results to C-CPB in patients undergoing isolated CABG. The potential efficacy of Mini-CPB is expected to be more evident in high-risk patients or in complex cardiac surgery requiring much longer cardiopulmonary perfusion.
ACCESSION #
40104127

 

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