False-Positive Results with a Commercially Available West Nile Virus Immunoglobulin M Assay -- United States, 2008

May 2009
MMWR: Morbidity & Mortality Weekly Report;5/8/2009, Vol. 58 Issue 17, p458
The article discusses the use of the West Nile virus (WNV) immunoglobulin M (IgM) capture enzyme-linked immunosorbent assay (ELISA) tests which resulted to false-positive results as investigated by the Centers for Disease Control and Prevention (CDC). As stated, the lot of WNV test kits available commercially were recalled in the U.S. It is noted that results from the assay must be confirmed by the plaque reduction neutralization tests (PRNT) or the CDC guidelines for proper diagnosis.


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