Simultaneous on-line size and chemical analysis of gas phase and particulate phase of cigarette mainstream smoke

Adam, Thomas; McAughey, John; McGrath, Conor; Mocker, Christoph; Zimmermann, Ralf
June 2009
Analytical & Bioanalytical Chemistry;Jun2009, Vol. 394 Issue 4, p1193
Academic Journal
This paper describes the combined set-up of on-line chemical analysis of gas phase by single-photon ionisation/resonance enhanced multiphoton ionisation–time-of-flight mass spectrometry (SPI/REMPI-TOFMS) and on-line particle size analysis by differential electrical mobility particle spectrometry (DMS 500) for the investigation of fresh cigarette mainstream smoke. SPI is well suited for the investigation of a great variety of organic species, whereas REMPI is highly sensitive for aromatic compounds. Gas phase measurements of filtered and unfiltered smoke are possible with the SPI/REMPI-TOFMS in order to determine the influence of the presence of particles on the chemical composition of the gas phase. Initial results are shown for the characterisation and comparison of three pure Virginia tobacco research cigarettes having filter ventilations of 0%, i.e. no filter ventilation, 35% and 70% ventilation. The three cigarette types are smoked under two different smoking regimes, a standard regime using puff parameters equivalent to the conventional International Standard Organisation regime and a more intense smoking regime. For the gas phase, qualitative puff-by-puff resolved yields of three selected compounds (acetaldehyde, phenol and styrene) are shown and compared. For particulate matter, particle number, count median diameter and total surface area are illustrated on a puff-by-puff basis. Yields of the chemicals analysed, puff number and surface area are in good agreement with the intensity of the smoking regime and the dilution of smoke by filter ventilation. However, gaseous compounds are influenced differently, depending whether an absolute particle filter is present or not, i.e. they can be totally removed (phenol), partially removed (styrene) or not affected (acetaldehyde). For particle analysis, the count median diameter decreases from puff to puff and is strongly dependent on the smoking regime and ventilation rate. Thereby, 0% ventilated cigarettes smoked under the intense regime result in the smallest count median diameters of ca. 180 nm, whereas 70% ventilated cigarettes smoked with a standard regime lead to the largest values of up to 280 nm. As particle diameter increases, particle number decreases as a consequence of increasing time for particle coagulation.


Related Articles

  • Spectroscopy of AlAr and AlKr from 31 000 cm-1 to the ionization limit. Heidecke, Scott A.; Fu, Zhenwen; Colt, John R.; Morse, Michael D. // Journal of Chemical Physics;8/1/1992, Vol. 97 Issue 3, p1692 

    Spectra of jet-cooled AlAr and AlKr have been collected over the range from 31 000 cm-1 to the ionization limit, using the technique of resonant two-photon ionization spectroscopy with mass spectrometric detection. Adiabatic ionization potentials have been accurately measured for both molecules,...

  • An ultrashort-duration, high-repetition-rate pulse source for laser ionization/mass spectrometry. Uchimura, T.; Nakamura, N.; Imasaka, T. // Review of Scientific Instruments;Jan2012, Vol. 83 Issue 1, p014101 

    This paper describes a sample inlet system with several advantages over other pulsed valves, as applied to resonance-enhanced multiphoton ionization/time-of-flight mass spectrometry. The nozzle is based on online concentration by analyte adsorption/laser desorption (online COLD), where a...

  • Molecular characterization and phylogenetic analysis of a novel glutenin gene (Dy10.1t) from Aegilops tauschii. Yanzhen Zhang; Qiaoyun Li; Yueming Yan; Jigang Zheng; Xueli An; Yinghua Xiao; Aili Wang; Yuhe Pei; Haibo Wang; Hsam, Sai L. K.; Zeller, Friedrich J. // Genome;Jul2006, Vol. 49 Issue 7, p735 

    A novel y-type high molecular mass glutenin subunit (HMM-GS) possessing a mobility that is slightly slower than that of the subunit Dy10 obtained by SDS–PAGE, named Dy10.1t, in the wild wheat Aegilops tauschii was identified by 1- and 2-dimensional gel electrophoresis, capillary...

  • Creating, detecting and locating ultracold molecules in a surface trap. Tscherneck, M.; Kleinert, J.; Haimberger, C.; Holmes, M. E.; Bigelow, N. P.; Wu, W. // Applied Physics B: Lasers & Optics;May2005, Vol. 80 Issue 6, p639 

    Ultracold molecules have been produced by photoassociation of Cs atoms trapped in a mirror magneto-optical trap. The molecules were detected by resonantly enhanced multi-photon ionization followed by time-of-flight mass spectroscopy. The time-of-flight ofatomic and molecular ions was...

  • An ion pulse ionization chamber for spectrometric measurements of low surface α activities. Gavrilyuk, Yu. M.; Gangapshev, A. M.; Kazalov, V. V.; Kuz'minov, V. V.; Panasenko, S. I.; Ratkevich, S. S. // Instruments & Experimental Techniques;Mar2009, Vol. 52 Issue 2, p173 

    The design of a pulse ionization chamber for measuring the surface αactivity of various samples is described. When used together with the appropriate methods for recording and processing the signals, a low-background spectrometer based on this chamber is able to ensure a high sensitivity in...

  • Recent problems and advances in mass spectrometry (Review). Lebedev, A.; Zaikin, V. // Inorganic Materials;Dec2008, Vol. 44 Issue 14, p1482 

    Advances in mass spectrometry, including the ionization and ion-separation methods, and its applications in various branches of science and human activity are overviewed.

  • Computational mass spectrometry for metabolomics: Identification of metabolites and small molecules. Neumann, Steffen; Böcker, Sebastian // Analytical & Bioanalytical Chemistry;Dec2010, Vol. 398 Issue 7/8, p2779 

    The identification of compounds from mass spectrometry (MS) data is still seen as a major bottleneck in the interpretation of MS data. This is particularly the case for the identification of small compounds such as metabolites, where until recently little progress has been made. Here we review...

  • Nanomaterials in mass spectrometry ionization and prospects for biological application. Zhong Guo; Ganawi, Amel A. A.; Qiang Liu; Lin He // Analytical & Bioanalytical Chemistry;Jan2006, Vol. 384 Issue 3, p584 

    The rapid development of nanotechnology has revolutionized scientific developments in recent decades. Mass spectrometry (MS) measurements are no exception and have benefited greatly from integration of nanomaterials in every step of analysis. This brief review summarizes recent developments in...

  • Precise impurity analysis of Cu films by GDMS: relation between negative substrate bias voltage and impurity ionization potentials. Lim, J.W.; Mimura, K.; Isshiki, M. // Applied Physics A: Materials Science & Processing;2005, Vol. 80 Issue 5, p1105 

    Cu films were deposited on Si(100) substrates by applying a negative substrate bias voltage using the non-mass-separated ion beam deposition method. Glow-discharge mass spectrometry was used to determine the impurity concentrations of the deposited Cu films and the 6N Cu target. It was found...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics