TITLE

Resistencia inducible a clindamicina en Staphylococcus aureus meticilino resistente

AUTHOR(S)
MONTOYA C., IRENE; MIRA O., MAGDALENA; ÁLVAREZ A., ISABEL; COFRÉ G., JOSÉ; COHEN V., JACOB; DONOSO W., GLORIA; TORRES T., JUAN PABLO
PUB. DATE
January 2009
SOURCE
Revista Chilena de Pediatría;ene/feb2009, Vol. 80 Issue 1, p48
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: The increase in methicillin-resistant Staphylococcus aureus (MRSA) infections has limited the use of efective available antibiotics. Clindamycin, an alternative against MRSA, might have inducible resistance that is not detected by common antibiograms. The disk diffusion method (D-test) detects the inducible resistance. Objetive: To establish the frecuency of inducible resistance in MRSA from blood and secretion samples obtained from hospitalyzed patients. Methods: Prospective and descriptive research, including MRSA positive blood and secretion samples from patients of Hospital Luis Calvo Mackenna, between July 2005-July 2006. A D-test was performed to the samples. Results: 220 MRSA samples were obtained and D-test was performed on 155 of them. 80% of the samples came from tracheobronquial secretion and 90% had used antibiotics. From all analyzed MRSA isolates, 32 (20.6%) were Clindamycin susceptible and 14 (43.8%) had Clindamycin inducible resistance (D-test+) Conclusions: A high percentage of MRSA Clindamycin resistant was found. From MRSA Clindamycin susceptible, 43.8% had Clindamycin inducible resistance (D test+). D-test was implemented in the Microbiology Laboratory at Hospital Luis Calvo Mackenna, allowing the identification of MRSA isolates suceptible to Clindamicyn treatment.
ACCESSION #
39764572

 

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