Subdiagnostische Depressionen

U. Hegerl; P. Schönknecht
May 2009
Der Nervenarzt;May2009, Vol. 80 Issue 5, p532
Academic Journal
Zusammenfassung  Mit minoren Depressionen, subsyndromalen Depressionen und unterschwelligen Depressionen werden in der ambulanten Versorgung häufige depressive Syndrome bezeichnet, die die Diagnosekriterien einer depressiven Störung nicht erfüllen, jedoch mit einer erheblichen Beeinträchtigung im psychosozialen Funktionsniveau einhergehen. Dargestellt wird die Evidenzlage zur Wirksamkeit von Pharmakotherapie, Psychotherapie und versorgungsqualitätverbessernden Interventionen. Kritisch diskutiert wird in diesem Zusammenhang der Ansatz, aus Placebo-Verum-Differenzen auf die klinische Relevanz von Antidepressivatherapien zu schließen. Bei insgesamt ungenügender Evidenzlage werden Überlegungen für ein pragmatisches Vorgehen in der Versorgung dieser Patienten vorgestellt.


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