TITLE

Spatial Temporal Image Correlation Spectroscopy (STICS) for Flow Analysis with Application for Blood Flow Mapping (abstract)

AUTHOR(S)
Rossow, Molly; Mantulin, William M.; Gratton, Enrico
PUB. DATE
April 2009
SOURCE
AIP Conference Proceedings;4/19/2009, Vol. 1119 Issue 1, p239
SOURCE TYPE
Conference Proceeding
DOC. TYPE
Article
ABSTRACT
It is important for surgeons to be able to measure blood flow in exposed arterioles during surgery. We report our progress in the development of an optical technique that will measure blood flow in surgically exposed blood vessels and enable previously difficult measurements. By monitoring optical fluctuations, the optical technique, based on Spatial Temporal Image Correlation (STICS), will directly measure the velocity of micron-scale particles—such as red blood cells. It will complement existing technology and provide qualitative measurements that were not previously possible. It relies on the concept that blood, when viewed on a small enough scale, is an inhomogeneous substance. Individual blood cells passing between a near-infrared light source and a detector will cause fluctuations in the transmitted optical signal. The speed, direction, and flow pattern of blood cells can be determined from these optical fluctuations. We present a series of computer simulations and experiments on phantom and animal systems to test this technique’s ability to map complex flow patterns.
ACCESSION #
39354946

 

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