TITLE

Treatment Implications

AUTHOR(S)
Krishnan-Sarin, Suchitra; O'Malley, Stephanie; Krysta, John H.
PUB. DATE
December 2008
SOURCE
Alcohol Research & Health;2008, Vol. 31 Issue 4, p400
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Developing pharmacotherapies to treat alcohol dependence and associated health problems traditionally has been based on gaining a better understanding of the neuroscience underlying alcoholdrinking behavior. To date, three medications have been approved for the treatment of alcohol dependence: disulfiram (Antabuse®), naltrexone (Revia®, Vivitrol®, and Naltrel®), and acamprosate (Campral®). However, these medications have modest efficacy, and there is a great need for newer medications that target different neurochemical systems and which could be used either as adjunctive treatments or to treat subpopulations of drinkers. Furthermore, it also is important to improve current treatment options by understanding and incorporating differences in how people with certain genes respond to medication (i.e., pharmacogenetic differences).
ACCESSION #
39231459

 

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