The Role of Selected Factors in the Development and Consequences of Alcohol Dependence

Gilbertson, Rebecca; Prather, Robert; Nixon, Sara Jo
December 2008
Alcohol Research & Health;2008, Vol. 31 Issue 4, p389
Academic Journal
Gender, family history, comorbid psychiatric and substance use disorders, and age all influence a person's risk for alcoholism. In addition, these factors interact with alcoholism to influence neurocognitive functioning following detoxification. This article examines these factors and considers how they interact with each other. This complexity reinforces the need for both animal and human studies and suggests multiple factors that may be sensitive to differential prevention, intervention, and treatment efforts. Thus, it is imperative that hypothesisdriven research designs be directed to identifying the relative potency of these factors and their interactions.


Related Articles

  • Alcohol Dependence, Withdrawal, and Relapse. Becker, Howard C. // Alcohol Research & Health;2008, Vol. 31 Issue 4, p348 

    Continued excessive alcohol consumption can lead to the development of dependence that is associated with a withdrawal syndrome when alcohol consumption is ceased or substantially reduced. This syndrome comprises physical signs as well as psychological symptoms that contribute to distress and...

  • Alcoholism--What Should I Know About It?  // American Family Physician;2/1/2005, Vol. 71 Issue 3, p1 

    Offers information on alcoholism. Medical conditions associated with alcoholism; Signs and symptoms of alcohol withdrawal syndrome; Efficacy of detoxification in treating alcoholism.

  • Who Is at Risk? Grant, Kathleen A.; Stafford, James; Thiede, Allison; Kiley, Caitlin; Odagiri, Misa; Ferguson, Betsy // Alcohol Research & Health;2008, Vol. 31 Issue 4, p289 

    Alcohol abuse and dependence are human conditions for which no full equivalent exists in animals. Nevertheless, animal models frequently are used to study various aspects of alcohol dependence that cannot be easily or ethically assessed in humans, including neurobiological mechanisms underlying...

  • Alcohol-Related Neurodegeneration and Recovery. Crews, Fulton T. // Alcohol Research & Health;2008, Vol. 31 Issue 4, p377 

    Human studies have found alcoholics to have a smaller brain size than moderate drinkers; however, these studies are complicated by many uncontrollable factors, including timing and amount of alcohol use. Animal experiments, which can control many factors, have established that alcohol can cause...

  • MOLECULAR MECHANISMS OF TOLERANCE. Pietrzykowski, Andrzej Z.; Treistman, Steven N. // Alcohol Research & Health;2008, Vol. 31 Issue 4, p301 

    The article discusses the molecular mechanisms involved in alcohol tolerance. Accordingly, tolerance has been divided into acute, rapid and chronic, which are based on how long after exposure to alcohol tolerance develops. None of the known molecular mechanisms can serve as a sole marker for a...

  • Drinking Games: Can Russia Admit It Has a Problem? Brown, Heidi // World Policy Journal;Jun2011, Vol. 28 Issue 2, p111 

    The article discusses alcoholism in the Russian Federation, considering its impact on Russian society and economic development. It discusses the history of alcohol consumption in Tsarist Russia and the Soviet Union and proposes that high levels of alcoholism made ruling the lower classes easier....

  • Avoidance of Alcohol-Related Stimuli Increases During the Early Stage of Abstinence in Alcohol-Dependent Patients. Vollstädt-Klein, Sabine; Loeber, Sabine; Von der Goltz, Christoph; Mann, Karl; Kiefer, Falk // Alcohol & Alcoholism;Sep/Oct2009, Vol. 44 Issue 5, p458 

    Aims: The aim of this study was to analyse initial orienting processes as well as maintenance of attention towards alcohol cues in recently detoxified alcoholics and light social drinkers. Furthermore, we investigated the influence of pre-treatment alcohol consumption and abstinence duration...

  • Implementation and clinical audit of alcohol detoxification guidelines. Taylor, Bob // British Journal of Nursing;1/12/2006, Vol. 15 Issue 1, p30 

    This article describes the implementation and clinical audit of alcohol detoxification guidelines at the Royal Cornwall Hospital. The progress in developing a hospital alcohol strategy as recommended by the Royal College of Physicians (2001) is also reviewed. The Clinical Institute Withdrawal...

  • MAST e AUDIT. Avaliação de Características Psicométricas em Doentes com Dependência de Álcool. FONTE, Aníbal; MOTA-CARDOSO, Rui // Acta Medica Portuguesa;Jul/Aug2013, Vol. 26 Issue 4, p335 

    Introduction/Objective: To evaluate the correlation between scores on the MAST and AUDIT in patients hospitalized for detoxification from alcohol dependence and consider if the intensity of those scores reflect the severity of dependence and problems related to alcohol use. Material and Methods:...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics