Signal Transmission in the Nervous System

Clapp, Peter; Bhave, Sanjiv V.; Hoffman, Paula L.
December 2008
Alcohol Research & Health;2008, Vol. 31 Issue 4, p318
Academic Journal
The article offers information on the signal transmission mechanisms and components in the human nervous system. The central component of the nervous system is the nerve cell or neuron which has three structural parts, the dendrite, cell body and axon. The authors cite that electrical signal transmission within neurons is based on voltage differences between the inside and outside of the cell. Signal transmission between cells, the role of excitation and the two classes of neutrotransmitter receptors are also discussed


Related Articles

  • Molecular neurobiology: Chained together. Wiedemann, Claudia // Nature Reviews Neuroscience;Nov2007, Vol. 8 Issue 11, p814 

    The article focuses on a study on the positioning of endocytic zones (EZs) and postsynaptic density (PSD). In this study, the researchers employed hippocampal neurons and combined live-cell imaging with quantification methods and electrophysiological studies to clarify the molecular machinery of...

  • Signal propagation in feedforward neuronal networks with unreliable synapses. Guo, Daqing; Li, Chunguang // Journal of Computational Neuroscience;Jun2011, Vol. 30 Issue 3, p567 

    In this paper, we systematically investigate both the synfire propagation and firing rate propagation in feedforward neuronal network coupled in an all-to-all fashion. In contrast to most earlier work, where only reliable synaptic connections are considered, we mainly examine the effects of...

  • Opposing functions of two sub-domains of the SNARE-complex in neurotransmission. Weber, Jens P.; Reim, Kerstin; Sørensen, Jakob B. // EMBO Journal;8/4/2010, Vol. 29 Issue 15, p2477 

    The SNARE-complex consisting of synaptobrevin-2/VAMP-2, SNAP-25 and syntaxin-1 is essential for evoked neurotransmission and also involved in spontaneous release. Here, we used cultured autaptic hippocampal neurons from Snap-25 null mice rescued with mutants challenging the C-terminal,...

  • The biology of winning Understanding the chemistry. Silberstein, Nina // Alive: Canada's Natural Health & Wellness Magazine;Feb2007, Issue 292, p68 

    The article talks about the scientific study of the brain and nervous system which sheds light on why some people are highly successful and talented. Neuroscientists believe that brain function is the combined result of millions of nerve cells communicating with each in the brain by releasing...

  • Behavioral choice by presynaptic inhibition of tactile sensory terminals. Gaudry, Quentin; Kristan, Jr., William B. // Nature Neuroscience;Nov2009, Vol. 12 Issue 11, p1450 

    When presented with multiple stimuli, animals generally choose to respond only to one input. The neuronal mechanisms determining such behavioral choices are poorly understood. We found that the medicinal leech had greatly diminished responses to moderate mechanosensory input as it fed. Feeding...

  • From glutamate co-release to vesicular synergy: vesicular glutamate transporters. El Mestikawy, Salah; Wallén-Mackenzie, Åsa; Fortin, Guillaume M.; Descarries, Laurent; Trudeau, Louis-Eric // Nature Reviews Neuroscience;Apr2011, Vol. 12 Issue 4, p204 

    Recent data indicate that 'classical' neurotransmitters can also act as co-transmitters. This notion has been strengthened by the demonstration that three vesicular glutamate transporters (vesicular glutamate transporter 1 (VGLUT1), VGLUT2 and VGLUT3) are present in central monoamine,...

  • Acute and gradual increases in BDNF concentration elicit distinct signaling and functions in neurons. Ji, Yuanyuan; Yuan Lu; Feng Yang; Wanhua Shen; Tina Tze-Tsang Tang; Linyin Feng; Duan, Shumin; Bai Lu // Nature Neuroscience;Mar2010, Vol. 13 Issue 3, p302 

    Extracellular factors may act on cells in two distinct modes: an acute increase in concentration as a result of regulated secretion, or a gradual increase in concentration when secreted constitutively or from a distant source. We found that cellular responses to brain-derived neurotrophic factor...

  • Synaptic transmission: On the probability of release. Flight, Monica Hoyos // Nature Reviews Neuroscience;Oct2008, Vol. 9 Issue 10, p736 

    The article presents a study on the level of depolarization in local dendrites as a major determinant of the basal probability of neurotransmitter release (pr). It states that to find out how dendritic activity might change the basal (pr), the authors used a stimulation protocol that elevated...

  • Development: Bricks for different houses. Wiedemann, Claudia // Nature Reviews Neuroscience;Oct2007, Vol. 8 Issue 10, p737 

    The article reports on several of the factors affecting axonal and dendritic development. The author cites the supply of membrane components to growth cones by the secretory pathway as one of the requirements for the outgrowth of dendrites and axons. However, there is no credible explanation to...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics