December 2008
Alcohol Research & Health;2008, Vol. 31 Issue 4, p316
Academic Journal
The article discusses the use of animal models in investigating the neurobiological changes produced by chronic alcohol exposure. It is noted that most of the human behaviors that define the DSM-IV diagnosis of alcohol dependence and which reflect essential characteristics of alcohol addiction such as compulsive drug seeking and drug use even in the face of negative health and social consequences cannot be directly modeled in animals. These animal models used include withdrawal-induced drinking mode, the alcohol deprivation effect model and the reinstatement model.


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