December 2008
Alcohol Research & Health;2008, Vol. 31 Issue 4, p303
Academic Journal
The article focuses on the conceptual framework called allostasis which is used by addiction researchers to refer to the development of tolerance. The concept wasdeveloped in the late 1980s to explain basic physiological mechanisms in human epidemiological findings and then extended to include stress and anxiety. It is noted that allostatic principles may be used for a better understanding of the relationship between alcohol tolerance and dependence.


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