Clinical trial registries becoming a reality, but long-term effects remain uncertain

Collier, Roger
May 2009
CMAJ: Canadian Medical Association Journal;5/12/2009, Vol. 180 Issue 10, p1007
Academic Journal
The article discusses the uncertainty of the long-term effects of clinical trial registration in the U.S. The advocates and registries of the scheme have increased including states government and editors of high-profile medical journals. However, some are concerned that the publishing incentives and mandatory-registration laws will not assure the change of the culture. A research institute also reveals that failure to include scientific investigators in the trial will result to publication bias. Another issue about the registration scheme is its availability because only high-income countries can do it reasonably.


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