Critical evaluation of sample pretreatment techniques

Hyötyläinen, Tuulia
June 2009
Analytical & Bioanalytical Chemistry;Jun2009, Vol. 394 Issue 3, p743
Academic Journal
Sample preparation before chromatographic separation is the most time-consuming and error-prone part of the analytical procedure. Therefore, selecting and optimizing an appropriate sample preparation scheme is a key factor in the final success of the analysis, and the judicious choice of an appropriate procedure greatly influences the reliability and accuracy of a given analysis. The main objective of this review is to critically evaluate the applicability, disadvantages, and advantages of various sample preparation techniques. Particular emphasis is placed on extraction techniques suitable for both liquid and solid samples. [Figure not available: see fulltext.]


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