TITLE

A hydrodynamic switch: Microfluidic separation system for magnetic beads

AUTHOR(S)
Weddemann, A.; Wittbracht, F.; Auge, A.; Hütten, A.
PUB. DATE
April 2009
SOURCE
Applied Physics Letters;4/27/2009, Vol. 94 Issue 17, p173501
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
In this work a device for separating small magnetic particles in continuous flow is introduced, consisting of two microfluidic channels that are connected by a junction channel. Applying two different flow rates, particles can be separated combining hydrodynamic and magnetophoretic effects. The two different flow rates introduce an additional degree of freedom that enables the microfluidic geometry to act as a hydrodynamic switch that can overcome diffusive contributions making the device applicable for particles of the size scale below 100 nm. Theoretical predictions based on finite element methods are compared to experimental observations.
ACCESSION #
38712350

 

Related Articles

  • Vortex breakdown in spherical gap. Bar-Yoseph, P.; Seelig, S.; Solan, A.; Roesner, K. G. // Physics of Fluids (00319171);Jun87, Vol. 30 Issue 6, p1581 

    A finite element solution of the flow between rotating spheres shows a vortex breakdown for Reynolds numbers exceeding a critical value. The result is in agreement with published results for a vortex breakdown in a cylindrical enclosure.

  • FIC/FEM Formulation with Matrix Stabilizing Terms for Incompressible Flows at Low and High Reynolds Numbers. Oñate, E.; Valls, A.; García, J. // Computational Mechanics;Oct2006, Vol. 38 Issue 4/5, p440 

    We present a general formulation for incompressible fluid flow analysis using the finite element method. The necessary stabilization for dealing with convective effects and the incompressibility condition are introduced via the Finite Calculus method using a matrix form of the stabilization...

  • A weighted reverse Cuthill-McKee procedure for finite element method algorithms to solve strongly anisotropic electrodynamic problems. Cristofolini, Andrea; Latini, Chiara; Borghi, Carlo A. // Journal of Applied Physics;Feb2011, Vol. 109 Issue 3, p033301 

    This paper presents a technique for improving the convergence rate of a generalized minimum residual (GMRES) algorithm applied for the solution of a algebraic system produced by the discretization of an electrodynamic problem with a tensorial electrical conductivity. The electrodynamic solver...

  • Vortex formation in a cavity with oscillating walls. Ovando, G.; Juárez, H.; Huelsz, G.; Ramos, E. // Physics of Fluids;Feb2009, Vol. 21 Issue 2, pN.PAG 

    The vortex formation in a two-dimensional Cartesian cavity, which their vertical walls move simultaneously with an oscillatory velocity and the horizontal walls are fixed pistons, is studied numerically. The governing equations were solved with a finite element method combined with an operator...

  • Three-Dimensional Analytical Model for an Axial-Field Magnetic Coupling. Dolisy, Bastien; Lubin, Thierry; Mezani, Smail; Lévêque, Jean // Progress in Electromagnetics Research M;2014, Vol. 35, p173 

    In this paper, we propose an analytical method for modeling a permanent magnets axial field magnetic coupling. The three-dimensional model takes into account the radial fringing effects of the coupler. The analytical solution requires resolving the Laplace equation in low permeability...

  • ANALYTICAL CALCULATION OF PARALLEL DOUBLE EXCITATION AND SPOKE-TYPE PERMANENT-MAGNET MOTORS; SIMPLIFIED VERSUS EXACT MODEL. Boughrara, Kamel; Lubin, Thierry; Ibtiouen, Rachid; Benallal, Mohamed N. // Progress in Electromagnetics Research B;2013, Vol. 48, p145 

    This paper deals with the prediction of magnetic field distribution and electromagnetic performances of parallel double excitation and spoke-type permanent magnet (PM) motors using simplified (SM) and exact (EM) analytical models. The simplified analytical model corresponds to a simplified...

  • Estimation of the magnetoelectric coefficient of a piezoelectric-magnetostrictive composite via finite element analysis. Sun, T. Y.; Sun, L.; Yong, Z. H.; Chan, H. L. W.; Wang, Y. // Journal of Applied Physics;Jul2013, Vol. 114 Issue 2, p027012 

    We proposed a new approach for estimating the magnetoelectric coefficient of magnetostrictive/piezoelectric composites via finite element analysis. With this method, the relationship between inputting magnetic field and outputting electric polarization for magnetoelectric composites could be...

  • Vortex Configurations in a Mesoscopic Superconducting Ring Structure: A Finite-Element Analysis. Peng, Lin; Wei, Zejiang; Liu, Yongsheng; Fang, Yangfu; Cai, Chuanbing // Journal of Superconductivity & Novel Magnetism;May2014, Vol. 27 Issue 5, p1217 

    The time-dependent Ginzburg-Landau equations have been solved numerically by a finite-element analysis for a mesoscopic superconducting ring structure. For given applied magnetic fields we have simulated the dynamical behavior of the penetrating magnetic vortices into the superconductor....

  • Research on an Axial Magnetic-Field-Modulated Brushless Double Rotor Machine. Ping Zheng; Zhiyi Song; Jingang Bai; Chengde Tong; Bin Yu // Energies (19961073);Sep2013, Vol. 6 Issue 9, p4799 

    Double rotor machine, an electronic continuously variable transmission, has great potential in application of hybrid electric vehicles (HEVs), wind power and marine propulsion. In this paper, an axial magnetic-field-modulated brushless double rotor machine (MFM-BDRM), which can realize the speed...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics