TITLE

A hydrodynamic switch: Microfluidic separation system for magnetic beads

AUTHOR(S)
Weddemann, A.; Wittbracht, F.; Auge, A.; Hütten, A.
PUB. DATE
April 2009
SOURCE
Applied Physics Letters;4/27/2009, Vol. 94 Issue 17, p173501
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
In this work a device for separating small magnetic particles in continuous flow is introduced, consisting of two microfluidic channels that are connected by a junction channel. Applying two different flow rates, particles can be separated combining hydrodynamic and magnetophoretic effects. The two different flow rates introduce an additional degree of freedom that enables the microfluidic geometry to act as a hydrodynamic switch that can overcome diffusive contributions making the device applicable for particles of the size scale below 100 nm. Theoretical predictions based on finite element methods are compared to experimental observations.
ACCESSION #
38712350

 

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