TITLE

Pathophysiology and Treatment of Radiation-Induced Brachial Plexopathy

AUTHOR(S)
Topkan, Erkan; Önal, H. Cem; Yavuz, M. Nur; Yavuz, A. Aydın
PUB. DATE
September 2008
SOURCE
International Journal of Hematology & Oncology / UHOD: Uluslarar;Sep2008, Vol. 18 Issue 3, p180
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Radiation therapy is a well proven effective treatment modality in the management of various cancers. However, radiation therapy has potentially adverse effects on several tissues including central and peripheral nervous systems. Radiation- induced brachial plexopathy is a rare but challenging complication of RT in patients undergoing chest, axillary, and neck irradiation because of myriad of primary or malignant tumors of these region. It is a progressive disease state which may lead to devastating sensorial and motor malfunctions. Currently, there is no generally accepted treatment method, but non-narcotic and narcotics and anesthetic interventions for grade 1 and 2 lesions are suggested. In grade 3 and 4 injuries, surgical interventions to prevent fibrosis of the vascular supply to the nerves and to release nerves from fibrotic constrictions should be considered.
ACCESSION #
38590929

 

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