Rektal Skuamöz Hücreli Karsinom: Bir Olgu Sunumu ve Literatürün Gözden Geçirilmesi

Küçükzeybek, Yüksel; Görümlü, Gürbüz; Cengiz, Ercüment; Karaca, Burçak; Erten, Çiğdem; Gül, M. Kemal; Tekin, Fatih; Kazandi, A. Can; Karabulut, Bülent
September 2008
International Journal of Hematology & Oncology / UHOD: Uluslarar;Sep2008, Vol. 18 Issue 3, p166
Academic Journal
Colorectal squamous cell carcinoma is an extremely rare tumor, comprising 0.01-0.025% of all colorectal cancers. A 55 years-old woman complaining of rectal bleeding was admitted to the hospital. An ulcerovegetan mass was seen in rectosigmoidoscopy and biopsies were taken. Histopathological examination revealed diagnosis as epidermoid cell carcinoma of rectum. Hypodense nodules were seen in different segments of liver in computerized tomography. After she was admitted to our hospital, rectosigmoidoscopy was repeated and biopsies were taken from ulcerovegetan mass in the rectum. The diagnosis was confirmed as squamous cell carcinoma. Paliative pelvic radiotherapy was delivered because of pain complain. The combination regimen including uracil-tegafur and carboplatin was administered because of the lack of standart chemotherapy regimens in this type cancer. After 3 cycles of chemotherapy, stable disease was defined in the radiological evaluation and her ECOG performance status improved. Therefore, we planned to continue with the same chemotherapy regimen. We detected radiologically progressive disease after six cycles of chemotherapy. We decided to report this case because of the rarity of squamous cell carcinoma of the rectum and the absence of standart chemotherapy regimen.


Related Articles

  • Proximal colon cancer in patients aged 51–60 years of age should be tested for microsatellites instability. A comment on the Revised Bethesda Guidelines. Urso, E.; Pucciarelli, S.; Agostini, M.; Maretto, I.; Mescoli, C.; Bertorelle, R.; Viel, A.; Rugge, M.; Nitti, D. // International Journal of Colorectal Disease;Aug2008, Vol. 23 Issue 8, p801 

    The Bethesda guidelines suggest to perform microsatellite instability (MSI) test in early onset rectal cancer and not in patients >50 years with proximal colon cancer. The aim of the study was to evaluate whether the risk of high MSI (MSI-H) is greater in proximal colon cancer of patients...

  • Aspirin therapy reduces the risk of colorectal ca. Cerrato, Paul L. // RN;Nov95, Vol. 58 Issue 11, p69 

    Presents a summary of a study on the effects of aspirin therapy to the risk of colorectal cancer, published in the `New England Journal of Medicine.'

  • Adjuvant therapy for colon and rectal cancer. Ratkin, Gary A. // American Family Physician;5/15/1997, Vol. 55 Issue 7, p2487 

    Reports that adjuvant chemotherapy and radiotherapy are indicated in patients with stages II and III rectal cancers. Tumor, node and distant metastasis staging of colon and rectal cancer; Adjuvant chemotherapy for colon cancer; Adjuvant chemotherapy and radiotherapy for rectal cancer;...

  • Chemotherapy and radiotherapy for cancer of the colon or...  // American Family Physician;5/15/1997, Vol. 55 Issue 7, p2495 

    Informs when chemotherapy and radiotherapy is for rectal or colon cancer. What is colon or rectal cancer staging; Meaning of stage I, II, III, IV cancer; Kind of chemotherapy used to treat colon and rectal cancer; Clinical research.

  • Cutaneous Metastases in Colorectal Cancer. Atalay, Can; Yilmaz, Kerim Bora // Medical Journal of Trakya University / Trakya Universitesi Tip F;2009, Vol. 26 Issue 4, p312 

    Objectives: Cutaneous metastases of colorectal cancer are rarely detected in clinical practice. This study aimed to evaluate the patients with cutaneous metastases of colorectal cancer in order to define their clinical presentation, clinical course, and prognosis. Patients and Methods: Patients...

  • A COX-2 inhibitor combined with chemoradiation of locally advanced rectal cancer: a phase II trial. Jakobsen, Anders; Mortensen, John Pløen; Bisgaard, Claus; Lindebjerg, Jan; Rafaelsen, Søren Rafael; Bendtsen, Vagn Ove // International Journal of Colorectal Disease;Mar2008, Vol. 23 Issue 3, p251 

    The aim of this study was to investigate the possible effect of a COX-2 inhibitor in addition to chemoradiation of locally advanced rectal cancer. The study included 35 patients with rectal adenocarcinoma. All patients had a tumor localised ≤10 cm from the anal verge and a circumferential...

  • Medical-Legal Risks of Incident Cancers After Clearing Colonoscopy. Rex, Douglas K.; Bond, John H.; Feld, Andrew D. // American Journal of Gastroenterology;Apr2001, Vol. 96 Issue 4, p952 

    Colonoscopy and polypectomy effectively reduce the incidence and mortality of colorectal cancer, but some patients present with fully developed cancers within 1-4 yr of a colonoscopy that apparently cleared the colon of neoplasia. These events may result in medical-legal action against...

  • Histopathological Prognostic Factors Influencing Long-Term Prognosis After Surgical Resection for Hepatic Metastases From Colorectal Cancer. Nagashima, Ikuo; Oka, Teruaki; Hamada, Chikuma; Naruse, Katsutoshi; Osada, Takuya; Muto, Tetsuichiro // American Journal of Gastroenterology;Mar1999, Vol. 94 Issue 3, p739 

    OBJECTIVE: We aimed to present new histopathological features of metastatic liver nodules as more reliable prognostic factors after surgical resection for colorectal metastatic cancer. METHODS: Clinicopathological features, including newly proposed histopathological ones, of 63 consecutive...

  • Clinicopathological differences of laterally spreading tumors arising in the colon and rectum. Miyamoto, Hideaki; Ikematsu, Hiroaki; Fujii, Satoshi; Osera, Shozo; Odagaki, Tomoyuki; Oono, Yasuhiro; Yano, Tomonori; Ochiai, Atsushi; Sasaki, Yutaka; Kaneko, Kazuhiro // International Journal of Colorectal Disease;Sep2014, Vol. 29 Issue 9, p1069 

    Purpose: Laterally spreading tumors (LST) have been recognized worldwide. The aim of our retrospective study was to evaluate the clinicopathological differences of LST arising in the colon and rectum. Methods: We investigated the clinical records of consecutive patients with LST that were...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics